图片: | |
---|---|
名称: | |
描述: | |
53 y/f with bilateral adnexal masses and anterior abdominal wall nodule and peritoneal effusion. Regular CT examination showed bilateral ovarian masse measuring 10 and 8 cm, respectively; lung negative, pancrease, gastric negative findings also. Patient has no previous malignant history.
《永恒爱恋老师友情帮助翻译》:女,53岁,双附件巨大肿块,之前有腹部质硬结节伴腹膜渗出物;CT检查示双侧附件巨大肿块,大小分别约为10cm和8cm,肺、胰腺、胃均无异常发现,患者无恶性肿瘤病史。
Core biopsy was performed for anterior andominal wall nodule.
行腹部质硬结节细针穿刺活检
Three core biopsy specimen showed benign fibroadipose tissue. Only one core demonstrate focal epithelial lining.
See the photos:
见图:
40x
100x
200x
400x
Please descript
请描述
1. Your analysis and impression for this core biopsy
1、您对此穿刺活检标本的分析和看法
2. If you want to order some stains, what stains will you order? Only three unstained slides are avaiable due to the scant tissue.
2、如果您觉得需要做免疫组织化学染色,会选择哪些标记,剩余的组织只可用来做三张染色。
本例点评:赵澄泉老师
(以下由:蔷薇老师友情帮助翻译!)53岁女性,双侧附件肿块,前腹壁结节,有腹水。常规CT检查显示双侧卵巢肿块分别为10cm及8cm;双肺、胰腺、胃未见特殊。患者无恶性肿瘤病史。
行前腹壁肿块粗针穿刺活检。
三条组织呈良性纤维脂肪组织。仅1条组织见局灶上皮被覆。
如图片所示:
请给出如下所述。
1 您对该活检的分析及诊断
2 如果需特殊染色,请列出那些特殊染色。由于组织有限,仅有3张白片。
点评专家:赵澄泉(113楼 链接:>>点击查看<< )
获奖名单:雅马哈(1楼 链接:>>点击查看<< )
wcz6962778 离线
The case discussion will include 5 groups of questions or steps:
1. 前腹壁结节 core biopsy (currently)
2. Showing you the IHC results of the core biopy specimen. How will you sign out the case?
3. 前腹壁结节biopsy again (not core biopsy). Showing you the frozen secetion. How will you sign out the frozen or how will you tell the surgon who is in the operation room ?
4. Showing you the photos of permenant H@E slides. your analysis for the case? what IHC stains will you order?
5. Showing you the photos of IHC stained slides. How will you sign out the case finally.
You need to attend the discussion for all 5 steps if you want to become the winner for this case discussion. Of cause I think the purpose for you to attend this activity is to learn pathology.
I will show you the next findings or questions in next weekend. One group of question per week.
Please help to translate above into Chinese. thanks, cz
译文:
本例的讨论将包括5组问题或分为5步:
1、前腹壁结节的粗针穿刺活检(目前的资料和图片)
2、为您提供粗针穿刺活检的免疫组化结果。然后您如何签发报告?
3、前腹壁结节再次活检(不再是粗针穿刺)。为您提供冰冻切片图。如何签发冰冻切片报告,或者,您怎样与等待在手术台上的手术医生交流?
4、为您提供常规石蜡切片。此时如何分析?要做哪些免疫组化?
5、为您提供免疫组化结果。如何签发最终报告。
如果您想要赢得本例的讨论,需要参加所有5步的讨论。当然,我认为参加讨论的目的是为了学习病理学。
下周我将为您提供下一步发现或提问。每周提供一组问题。(abin译)
It is 前腹壁结节 core biopsy, but not ovarian biopsy. It is easy for gynecologists to do the 前腹壁结节 core biopsy than the biopsy of the ovary. From the clinical point of view the 前腹壁结节 tumor and ovarian tumor should be the same.
译文:
这是前腹壁结节的粗针穿刺活检,不是卵巢活检。妇科医生很容易做前腹壁结节粗针穿刺活检,比卵巢活检容易。从临床角度,前腹壁结节与卵巢肿瘤应该是相同的。
The case discussion will include 5 groups of questions or steps:
1. 前腹壁结节 core biopsy (currently)
2. Showing you the IHC results of the core biopy specimen. How will you sign out the case?
3. 前腹壁结节biopsy again (not core biopsy). Showing you the frozen secetion. How will you sign out the frozen or how will you tell the surgon who is in the operation room ?
4. Showing you the photos of permenant H@E slides. your analysis for the case? what IHC stains will you order?
5. Showing you the photos of IHC stained slides. How will you sign out the case finally.
You need to attend the discussion for all 5 steps if you want to become the winner for this case discussion. Of cause I think the purpose for you to attend this activity is to learn pathology.
I will show you the next findings or questions in next weekend. One group of question per week.
Please help to translate above into Chinese. thanks, cz
翻译:
此例病例讨论包括五组问题或五个步骤。
1、前腹壁结节组织活检(当前的);
2、若给出组织活检标本的免疫组化结果,你将如何签署此例结果?
3、前腹壁结节再次活检(非穿刺活检)。若给出冰冻切片,你如何签署冰冻切片结果或者是你如何告诉手术室外科医生?
4、若给出固定后HE染色切片的图像,你对此例的分析是怎样的?你将选择怎样的免疫组化染色?
5、若给出免疫组化染色切片图像,你对此例将签署怎样的最终结果?
如果你想成为这个病例的赢家,你必须叁加所有这五个环节的讨论。当然,我想你参加这个活动的目的就是为了学习病理。
我将在下周末给出下一步的发现或者是问题,每周一组问题。
本例为女性患者,53岁,CT示双附件肿块,穿刺活检标本为腹腔前壁肿块。没有提示腹壁肿块与双附件的关系。肺、胰腺、胃均无异常发现,患者无恶性肿瘤病史。
穿刺活检三条组织 仅1条为内衬立方-低柱状上皮的囊壁样组织,大部分区域单层,局部呈2层,异型性不著,可见基底膜,囊壁较厚,呈明显两种结构,上皮下与卵巢皮质相似,而中外侧为纤维性囊壁。
如病变位于卵巢,应考虑为卵巢上皮性囊性病变,包括上皮性肿瘤、卵巢冠囊肿、子宫内膜异位症和包含囊肿等,本例组织学改变不支持子宫内膜异位和包含囊肿,内衬上皮缺乏黏液性上皮、子宫内膜样上皮特点,可排除。病变位于腹壁前部,也不支持卵巢冠囊肿;内衬上皮呈立方、低柱状、无纤毛,上皮下可见卵巢皮质样组织,也不支持浆液性上皮性肿瘤。综合上述,病变不支持卵巢的原发性病变。
腹腔衬覆上皮的囊性病变包括:肠源性囊肿、异位胰源性囊肿和腹膜间皮化生型囊肿(第二苗勒系统上皮性囊肿),肠源性囊肿内衬上皮内含黏液细胞,或类似肠黏膜,本例不支持;第二苗勒系统上皮性囊肿以浆液性囊性肿瘤最常见,形态结构与卵巢者相似,本例也不像。胰源性囊肿包括浆液性和黏液型两种,黏液性囊肿内衬黏液上皮,并见粘液腺体,浆液性囊肿内衬不典型浆液上皮,上皮下可见卵巢皮质样组织,ER、PR、a-inhinbin阳性。本例衬覆浆液样上皮,上皮下见卵巢皮质样组织,首先考虑异位胰源性浆液性囊肿,其次为腹腔浆液性囊腺瘤。可行ER、PR、CA125免疫组化进一步确诊。
symsymjulia 离线
Based on the requirement from the patient or clinician, the Tissue of Origin Test (from block) was performed by Pathwork Diagnostics (Redwood City, CA).
A. Most likely tissue of origin: PANCREAS (Degree of confidence: MODERATELY HIGH; Similarity Score-SS 41.6) (see note).
B. Tissues ruled out: Sarcoma, Breast, Non-Small Cell Lung, Bladder, Thyroid, Melanoma, Kidney, Hepatocellular, Hon-Hodgkin Lymphoma, Testicular Germ Cell, Prostate.
TISSUE OF ORIGIN TEST
TISSUE Similarity score:
Pancreas 41.6
Gastric 25.6
Colorectal 13.5
Ovarian 7.3
Sarcoma 3.8
Breast 1.8
Non-Small Cell Lung 1.0
Bladder 1.0
Thyroid 1.0
Melanoma 0.8
Kidney 0.8
Hepatocellular 0.7
Non-Hodgkin Lymphoma 0.6
Testicular Germ Cell 0.4
Prostate 0.4
NOTE:
An off-panel tumor type, such as cholangiocarcinoma and esophageal adenocarcinoma, CANNOT BE EXCLUDED by the Test.
Some one please help to translate the report about the tissue of origin test into chinese