不好意思，被误导了，看到第一眼，觉得没问题，不过总觉得赵老师不会出这么简单的问题吧，又看到小叶周围纤维胶原化，先想到腺病，疤痕样，所以想是硬化腺病。呵呵，现在明白了。思路还是没完全打开，看赵老师的帖子，要多动脑了。
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- Breast lobular lesions and stains ( cqz 7)
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本帖最后由 于 2008-12-27 12:12:00 编辑
For 天山望月 's beautiful flower, I took photos from one of my today's cases and sent here.
F1 100x
F2 200x
F3 400x
Middle aged women with core biopsy due to the abnormal mammogram imagines. Only lesion in three cores showed in the photos.
What do you think?
名称：图1
描述：图1
名称：图2
描述：图2
名称：图3
描述：图3
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本帖最后由 于 2008-12-26 13:42:00 编辑
| 以下是引用cqzhao在2008-12-24 1:59:00的发言：
I am doing breast core biopsy service this week. Give you another example of very focal ALH from my today' s cases.
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赵老师辛苦了!我们的乳腺穿刺病例较少，期待有机会分享您的许多病例，典型的和不典型的，都能给我们许多启示，引导横向思维，不断提高诊断水平。
送一束鲜花，深表谢意！
- 广州金域病理
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本帖最后由 于 2008-12-24 19:43:00 编辑
I am doing breast core biopsy service this week. Give you another example of very focal ALH from my today' s cases.
Just hope whoever read this topic from this web can think about the lesions in your practice. Do stains if you are not sure.
We should learn some priciple from the case study, but not only one case interpretation.
这周我做乳腺粗针穿刺活检。从我今天的病例中提供另一例非常局灶性的ALH。
希望看过这个主题贴的人在实际工作中能够考虑到这种病变，如果不确定，做免疫组化。
我们应该从病例学习中学到一些原则，而不只是一个病例解读。
____abin译
名称：图1
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名称：图2
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本帖最后由 于 2008-12-24 19:40:00 编辑
Dual stain (p120 and e-cad) for above case
Clearly it is ALH lesion. The H&E morphology is very minimal. It is very easy to be missed for every one.
ALH is the risk factor of cancers. Women can have more close follow up it we can diagnose the lesion, or excisional biopsy for women with core biopsy.
Can you say you never miss the samll lesions? This is why stains are important sometimes. I remember that we once had argument if stains are needed for lobular lesions in this web.
上述HE图片的IHC双标(p120 and e-cad)。
这是明确的ALH。HE形态学很微小。每个人都容易漏诊。
ALH是进展为浸润性乳腺癌的危险因素。如果诊断了这个病变，患者需要更密切随访，或粗针穿刺活检后作切除活检。你能说从未漏诊过这种微小病变？这就是为什么有时IHC非常重要的原因。记得我们曾经在这个网站上争论过小叶病变是否需要IHC。
____abin译
名称：图1
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45 y female for bilateral breast reduction:
Breast reduction is a surgery procedure, not a disease. Some women's breasts are large. They ask the surgeons to take out some of normal breast tissue to make their breast smaller for purpose of beauty. it is a kind of plastic or cosmetic surgery. Breast reduction is opposite of breast augmentation.
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本帖最后由 于 2008-12-21 22:15:00 编辑
Put here another case.
45 y female for bilateral breast reduction (about 900 grams for each side).
One section as the photo.
Our rule for breast reduction age 40 or above:
10 sections are submitted for microscopic examination for each side.
What do you think? How will you deal with this case?
名称：图1
描述：图1
