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患者56岁,乳腺穿刺诊断查到癌细胞,化疗几个疗程后做手术,手术后标本未找到肿物
病理报告:乳腺癌化疗后反应。
是否化疗能把肿物消除?穿刺诊断是否可以直接发?
请各位老师指点
liuhuanggao 离线
非妇科细胞学可以作为临床治疗的依据,甲状腺细针穿刺诊断了乳头状癌的也可以不用做冰冻,胸腹水影像学检查没有占位性病变的即使没有细胞块也一样可以报腺癌,现在总是有人唱衰细胞学,说细胞学这也不行那也不行,我看就是他自己不行,细胞病理学有一定局限性,这一点我们必须的承认,组织病理学难道就不受取材的影响?组织病理学难道就没有过诊断低诊断的?冰冻难道就没有假阳性假阴性的?就拿支气管刷片来说,细胞学阳性组织学阴性时有发生,难道此时还要看你组织学的脸呢?细胞学阳性组织学阴性,组织病理医师还跑过来向细胞病理医师请教呢,这在进修时都是亲眼所见,为什么有的医院临床医师只相信组织学不相信细胞学?因为这些医院病理科的所谓细胞病理医师就没有干过让临床医师相信的事,有时候还将临床往沟里带呢,这让人家怎么相信你?我进修时外院的胸腹水、细针穿刺样本都还往我所进修的医院送呢,这些医院有病理科为什么临床还让家属将样本送往我所进修的医院呢?大家想想看,就是因为这些医院看细胞的病理医师不行,得不到临床的信任,自己不行能怨谁呢?有生意尽让别人做了,我所在进修的医院病理科细胞室人家就是强,阳性率就是高,难怪外院的样本都往这里送呢,有些检验科看细胞学的都比一些所谓的病理医师强,人家细胞学还搞得有声有色,还有的人总是认为细胞学很简单,看看就会了,这种人必定做不了一个好的细胞病理医师,细胞学很有用处,细胞学是三维的组织学是二维的,如果有一天你能真正从三维的角度看细胞,这说明你细胞学入门了。
We have recently 2 cases with similar story, core biopsy dx was DCIS and lumpectomy found no cancer. Our approach was: multiple deeper sections to looking for scar or biopsy site granulation to make sure we got correct tissue/site, if not found, turned the block around (flip over) and cut again.
One case we did not find anything, multiple communication with surgeon and make sure he understand the situation. 2nd case, DCIS was found after flipped over the block.
Breast lesion here is a big deal, and complecated issue. First time biopsy usually (perfer tissue rather than cytology) left a small metal marker inside the biopsy site for future locatoin under X-ray. lumpectomy specimen comes to us with X-ray film showing the marker and lesion.
For your case, it certainly chemotherapy may kill (cure) the cancer, congradulations.