| 图片： | |
|---|---|
| 名称： | |
| 描述： | |
- B2766右乳肿物
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图8
| 姓 名： | ××× | 性别： | 女 | 年龄： | 32 |
| 标本名称： | |||||
| 简要病史： | 妊娠六个月右乳及右腋下各有一3cm肿物（镜下形态相同） | ||||
| 肉眼检查： | 右乳及有腋下肿物穿刺 | ||||
标签：乳腺浸润性癌 乳腺浸润性小叶癌 E-cadherin P120
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×参考诊断
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This is very interesting case with special cytomorphology. I notice the CK positive stain.
The key is to make sure it is a carcinoma first.
If it were my case, I would stain AE1/AE3, cam5.2, CK7.
If it is carcinoma, I would stain E-cad and p120 to make sure if it is a lobular ca.
Also will stain ER, PR, Her2.
If it is lobular ca, it is pleomorphic or signet ring type. It is not a classic type invasive lobular ca.
If it is not a lobular ca and if it is triple negative, I would stain ck14, ck17, ck5, EGFR to see if it is basal-like tumor
感谢cqzhao老师的指点啊，获益非浅
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CHENYINQIAO 离线
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| 以下是引用cqzhao在2010-7-18 5:22:00的发言：
This is very interesting case with special cytomorphology. I notice the CK positive stain. The key is to make sure it is a carcinoma first. If it were my case, I would stain AE1/AE3, cam5.2, CK7. If it is carcinoma, I would stain E-cad and p120 to make sure if it is a lobular ca. Also will stain ER, PR, Her2. If it is lobular ca, it is pleomorphic or signet ring type. It is not a classic type invasive lobular ca. If it is not a lobular ca and if it is triple negative, I would stain ck14, ck17, ck5, EGFR to see if it is basal-like tumor. |
- 挺挺花卉中，竹有节而啬花，梅有花而啬叶，松有叶而啬香，唯兰独并有之
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