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姓 名: | ××× | 性别: | 女 | 年龄: | 32 |
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简要病史: | 妊娠六个月右乳及右腋下各有一3cm肿物(镜下形态相同) | ||||
肉眼检查: | 右乳及有腋下肿物穿刺 |
This is very interesting case with special cytomorphology. I notice the CK positive stain.
The key is to make sure it is a carcinoma first.
If it were my case, I would stain AE1/AE3, cam5.2, CK7.
If it is carcinoma, I would stain E-cad and p120 to make sure if it is a lobular ca.
Also will stain ER, PR, Her2.
If it is lobular ca, it is pleomorphic or signet ring type. It is not a classic type invasive lobular ca.
If it is not a lobular ca and if it is triple negative, I would stain ck14, ck17, ck5, EGFR to see if it is basal-like tumor.