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以下是引用追逐太阳在2009-12-16 21:30:00的发言:
赵老师好! 我的意见是:低度恶性子宫内膜间质肉瘤,伴性索样分化。 |
I totally agree with your dx even though it is no IHC. This type of tumor is rare in clinical practice. If it were my case I will do some stains for sex cord markers. The purposes are to confirm dx and to get some personal experience. We order IHC based on the need and seldom consier the money issue. This is why there is big problem for health insurance in US. Ha, ha.
Anyway thank you very much for sharing the rare and interesing case, especially for the beautiful photos, cz
以下是引用hlzg在2009-12-16 22:50:00的发言:
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以下是引用szhou8在2009-12-15 22:13:00的发言:
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以下是引用cqzhao在2009-12-14 3:18:00的发言:
Do not need to 惭愧. Why do you think I 失望了. It is your case, but not mine. Just wonder how you signed out the case.
Thank you for sharing these beautiful photos. 没必要惭愧,为什么认为我失望了呢?它是你的例子,而不是我的。只是想知道你会怎样处理这个例子。 非常感谢分享。 |
Endometrial stromal tumor (uniform, oval shaped cells like proliferative endometrial stroma+small vescultures) with infiltrating borders=endometrial stromal sarcoma Some photos demonstrat cord, trabecular, and sertoliform tubular structure=like ovarian sex-cord component My impression is Low grade endometrial stroma sarcoma with sex cord like elements based on H&E photos above.. the main ddx: uterine tumor resemble ovarina sex-cord tumor. IHC: pck, ema (sex-cord component may be posiitve). calretinin, CD99 or inhibin: should have some positivity in sex cord componnet. SMA, desmin, or caldesmon to rule out smooth muscle tumor CD10 for stroma component. Very good case. | ||
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以下是引用追逐太阳在2009-12-13 13:27:00的发言:
惭愧!这个病例未做免疫组化,让赵老师失望了。 告 |
Do not need to 惭愧. Why do you think I 失望了. It is your case, but not mine.
Just wonder how you signed out the case.
Thank you for sharing these beautiful photos.
没必要惭愧,为什么认为我失望了呢?它是你的例子,而不是我的。只是想知道你会怎样发的病理报。
非常感谢分享。
以下是引用Dr_Lu在2009-12-13 15:20:00的发言:
这一例赵大夫分析得很透彻。 请教赵大夫一个问题:一直以来,我们的CD10抗体染子宫内膜间质肿瘤时显色不好,只有正常子宫内膜间质阳性,子宫内膜间质肉瘤时很难染出阳性,请问贵室用的CD10抗体是哪个公司生产的?哪一个克隆号?是否与染淋巴滤泡中心细胞的CD10为同一种抗体?染色时如何抗原修复? |
Dr. Lu,
Generally high grade sarcoma can have poor stain or loss of stain for CD10. We use the same CD10 antibody for staining. I will ask the lab and let you know the company.
Dr. Lu,
一般而言高级别肉瘤对CD10弱表达或不表达。我们同样使用CD10抗体染。我问问实验室然后告诉你公司。