图片: | |
---|---|
名称: | |
描述: | |
姓 名: | ××× | 性别: | 年龄: | ||
标本名称: | |||||
简要病史: | |||||
肉眼检查: |
50 岁妇女乳腺肿瘤2.5cm
. Fig 1-4. most areas of the tumor.
以下是引用xljin8在2009-11-18 6:27:00的发言: 2008-04-23 abin医师对浸润性小叶癌做了非常详尽的组织学和细胞学总结, 使我受益非浅。我把它储存在收藏夹量,以便温故知新。 更是敬佩Dr. Chao 乳腺病理诊断的丰富经验和非常感激对国内病理医师的仔细讲解和示教。 |
以下是引用xljin8在2009-11-14 13:17:00的发言:
非常感兴趣的病例,但是我有些疑问: 1)文献中有tubulolobular carcinoma 的名称,应该如何理解? 2)能否提供小管癌区域的免疫组化标记片? 3)诊断时是否因为浸润性小叶癌的恶性程度高而可忽略其他成分? |
Thank for your attention.
1) + 2): will show the IHC results of other areas and have some discussion one by one.
3)诊断时是否因为浸润性小叶癌的恶性程度高而可忽略其他成分?
No. We report all abnormal lesions in the reports in our hospital.
For example:
Invasive ductal or lobular ca
in site ca (DCIS or LCIS)
Atypical lesions: ADH, ALH, atypical papilloma, FEA
Will have one dx line to include all non-neoplastic breast lesions such as FCC, sclerosing adenosis, introductal papilloma, UDH, radial scar, CCC, calcification....
All of you are right about the tumor.
Stains for the main tumor or fig1 (question 1)
E-cad and P120
interpretaion of P120: lobular lesion-cytoplasmic stain; ductal lesion-membrane stain.
We will have the answers for others one by one soon.
skyliutong 离线
以下是引用SOS991229在2009-11-11 23:26:00的发言:
我们在平常工作中也会出现这种情况,我们就冠个总名:浸润性癌,部分区域为浸润性小叶癌,部分区域为浸润性导管癌。不知道赵老师那边是怎样规范的报告?还有是否国外在报告ER,PR时要报%吗?就像ki-67那样+>30%之类的吗?谢谢您! |
We do er/pr/her2/ki67 for all cases of invasive breast ca
I mentioned Her2 report before. I think the Her2 reort is similar among most hospitals in China and the US.
Currently we report ER/PR and ki67 as following.
ER/PR: H score:
example:
ER positive, H score 240 (0 10%; 1+10%; 2+10%; 3+70%)
H score count: (3x70=210)+(2x10=20)+(1x10=10)+(0x10=0) =240
Tumor cell proliferation index (Ki67):
Result 40%,
Index high (low: to 10%; moderate:11-25%; high:26-50%; very high:>50%)
Magee is a breast and gynecologic center. Our reports are very detailed. The report systems can be very variable in different hospitals.
Just for your reference