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Recently I noticed some topics related liquid based cytology (LBC) and conventional Pap smears (CP) in this website. We know that the price of LBC is higher than CP.
Hope we can discuss the disadvantage and advantage of both methods.
What methods are used in your hospitals?
What method you think should be used in China now or future?
Also I will find some data to let you know the main methods used in other main countries. As of May 1, 2008, the United Nations has 192 members. In China we mention 国外, which include more than 190 contries.
Thanks
cz
Ok. I showed you a lot of studies about comparsion between LBC and conventional Pap. Also I pasted current marketing about these two methods in the USA and some other countries.
Just let you know more information outside of China. If you read all papers and you will know which method is better and know why.
Thank all of you for the review and discuss of this topic. Especially thank 兰青风采 or 掌心0164 for your translation.
To 法师
Could you give a summary to compaare the advantage and disadventage of conventional smear and liquid based Pap test. in term of senstivity, specificity, difficulty or easy to read, price, cost effect, HPV test, automation, et al...
You can make a list
Thanks,
cz
以下是引用cqzhao在2009-4-11 19:49:00的发言:
To 法师 Could you give a summary to compaare the advantage and disadventage of conventional smear and liquid based Pap test. in term of senstivity, specificity, difficulty or easy to read, price, cost effect, HPV test, automation, et al... You can make a list Thanks, cz |
其实我没多少这方面的经验,也没权威的数据来说明这个问题,我仅根据平常的经验和本地的经济水平,人们对疾病的理解程度及从业人员技术水平来臆断的,如果条件容许,我倾向采用液基制片进行常规检测,在网站里我也发过一些传统制片的图片,虽然我们很努力的想做好,但就这么几例大家也会感觉到传统制片的缺陷带来的结果判断困难,有几例明显的HSIL,由于涂片模糊不清而没有信心直接报告.
|
液基制片 |
传统制片 |
HPV测定 | |
获得满意的涂片 |
较容易 |
难 |
- | |
阅片的难易程度 |
轻松 |
困难 |
- | |
标本远距离保存及运输 |
容易做到 |
难以保证质量 |
容易做到 | |
检测的灵敏度 |
高 |
相对较低(不容易获得满意的涂片) |
高 | |
检测的特异性 |
相对上皮内病变 |
高 |
高 |
低 |
相对HPV感染 |
一般 |
一般 |
高 | |
检测的设备要求 |
从一般到较高 |
简单 |
高 | |
对商业耗材的依赖 |
高 |
低 |
高 | |
对人员的要求 |
高 |
很高,特别需要多部门的配合 |
较高 | |
测试的价格 |
中等 |
低 |
较高 | |
标准化及质量控制 |
容易做到 |
难以做到 |
容易做到 | |
有规律的持续监测并指导临床及时处理 |
容易做到 |
容易做到 |
较难做到 |
感谢cqzhao老师引导我们进行这个讨论,在讨论中我们学到了很多.
Dear 法师 : Thank you very much. I appreciate your work attitude. Your summary is very good. From your table I can know that you spent a lot of your time and considered the issue very carefully.
Generally speaking LBC is more sensitive and specific for the detection of SIL and glandular lesions, and easy to read. However conventional pap tests can get good results if the slides are prepared well.
From floor 81, Australia, New zealand, and some 北欧 countries still use CP.
城北 mentioned in other topic:
In the US the amount of pathology service fee paid by insurance companies or medicaid or medicare is much less than that pathology required.
Pathology code for LBC and HC2 HPV test: about $100
But the true money for a Pap test
Reimbursement for Pap
CMS (Center for Medicare & Medicaid Service) National Limitation Amount (Medicare)
Conventional Liquid-Based
88164 $14.76 88142 $28.31
88147 $15.90 88174 $29.85
88148 $21.23 88175 $37.01
You can see it is very cheaper for a Pap test in the US. This is why many pathology departments do not like to do the Pap tests. However at least the price for LBC is two times of conventional Pap.