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liguoxia71 离线
listli1999 离线
Poorly differentiated carcinoma. I personally don'st favor small cell undifferentiated cancer because these cells are quite large (small cell carcinoma cells are <3x the size of lymphocytes), no typical molding, and have some cytoplasm, especially the last picture. Small cell carcinoma usually dont have much cytoplasm. The tumor cells are almost pleomorphic with ?squamous differentiation. If you cannot cut more sections for immunostains, can you destain H&E sections and restain with neuroendocrine markers ?
My experience is: you have to make decision of cancer or not cancer on H&E sections in the lung. Immunostains only help you with what type of cancer.