同意以上意见。

凭这张片诊断恶性肿瘤－鳞癌或者小细胞癌太危险了。组织太少，细胞人为变态较严重，是鳞状上皮细胞还是纤毛柱状上皮细胞还很难说，需结合临床如胸片，患者症状等考虑。先提示临床“活检组织中见少量异形细胞团，但变形严重，建议再取活检”为好。

细胞有变性，核结构不清，胞浆量不少，不敢报小细胞癌。可能是鳞状上皮的问题。

鳞化的纤毛柱状上皮，有非典型性，癌不够。试着这点标记看看如何？

鳞化的纤毛柱状上皮，有非典型性，癌不够。试着这点标记看看如何？

 Poorly differentiated carcinoma.  I personally don'st favor small cell undifferentiated cancer because these cells are quite large (small cell carcinoma cells are <3x the size of lymphocytes), no typical molding, and have some cytoplasm, especially the last picture.  Small cell carcinoma usually dont have much cytoplasm.  The tumor cells are almost pleomorphic with ?squamous differentiation.  If you cannot cut more sections for immunostains, can you destain H&E sections and restain with neuroendocrine markers ?

My experience is: you have to make decision of cancer or not cancer on H&E sections in the lung.  Immunostains only help you with what type of cancer.