细胞有变性，核结构不清，胞浆量不少，不敢报小细胞癌。可能是鳞状上皮的问题。

鳞化的纤毛柱状上皮，有非典型性，癌不够。试着这点标记看看如何？

鳞化的纤毛柱状上皮，有非典型性，癌不够。试着这点标记看看如何？

 Poorly differentiated carcinoma.  I personally don'st favor small cell undifferentiated cancer because these cells are quite large (small cell carcinoma cells are <3x the size of lymphocytes), no typical molding, and have some cytoplasm, especially the last picture.  Small cell carcinoma usually dont have much cytoplasm.  The tumor cells are almost pleomorphic with ?squamous differentiation.  If you cannot cut more sections for immunostains, can you destain H&E sections and restain with neuroendocrine markers ?

My experience is: you have to make decision of cancer or not cancer on H&E sections in the lung.  Immunostains only help you with what type of cancer.

同意，组织有一定程度挤压，组织结构、细胞形态均变形。先以不诊断恶性为好，建议再取活检。