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lfl001200546 离线
姓 名: | ××× | 性别: | 年龄: | ||
标本名称: | 女,42岁,发现宫颈肿块15天,5*5*2CM | ||||
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肉眼检查: |
jiangxiaoyu 离线
When you see myxoid changes in myometrium like this case, two important differential diagnoses should be first considered. 1) Myxoid low grade endometrial stromal sarcoma and 2) myxoid leiomyosarcoma. I would ask more low power photos to show the interface between this mass and adjacent normal myometrium and also to show if there is invagination or projection into large vessle lumens. These are VERY IMPORTANT features to evaluate endometrial stromal sarcoma. I also suggest to have immunostain for CD10, SMA and desmin done to know the origin of these cells.
(子宫肌层的粘液样病变,首先应该考虑两个鉴别诊断:1)粘液样低度恶性子宫内膜间质肉瘤和2)粘液样平滑肌肉瘤。我需要更多低倍图像,显示肿块与相邻正常子宫肌层的交界情况,以及是否存在陷入或穿入大血管腔内。这对评价子宫内膜间质肉瘤非常重要。我也建议做免疫染色:CD10、SMA和Desmin以判断这些细胞的起源。abin译)
liguoxia71 离线
lfl001200546 离线
有免疫组化结果吗?
宫颈的平滑肌肉瘤非常罕见(国外文献多是个案报道),粘液性者应该更罕见了。如果诊断成立,这可能是国内第一例,应该报道的。
有兴趣者可参考:
1、Case of the Week #92
http://www.pathologyoutlines.com/caseofweek/case200792.htm
2、Leiomyosarcoma of the cervix.
PMID: 14675691
3、Leiomyosarcoma of the uterine cervix.
PMID: 9600826
华夏病理/粉蓝医疗
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lfl001200546 离线
以下是引用abin在2008-2-25 21:46:00的发言: 有免疫组化结果吗? 宫颈的平滑肌肉瘤非常罕见(国外文献多是个案报道),粘液性者应该更罕见了。如果诊断成立,这可能是国内第一例,应该报道的。 有兴趣者可参考: 1、Case of the Week #92 http://www.pathologyoutlines.com/caseofweek/case200792.htm 2、Leiomyosarcoma of the cervix. PMID: 14675691 3、Leiomyosarcoma of the uterine cervix. PMID: 9600826 |
lfl001200546 离线