Of cause I can buy it if you want to call invasive lobular ca with focal 小管-小叶癌.

如果称为浸润性小叶癌，我当然也能接受。

 In clinical practice, often we can have some tumors showing some complicated features.

Clinically there is no much difference for what you call in this case.

I would call

- invasive lobular ca with focal tubular structures. or invasive lobular ca with focal ductal ca.

-Lobular ca in situ

- lymph node is positive for lobular ca

with a comment to explane the situation.

Thank for sharing the case.

Just for your reference

临床实践中，我们常常见到某些肿瘤显示一些复杂特征。

本例具体称为什么，在临床上并无太大差异。

我可能会称为：

-浸润性小叶癌伴局灶小管结构。或浸润性小叶癌伴局灶导管癌。

-小叶原位癌。

-淋巴结阳性，为小叶癌

加备注进一步解释这种情形。

谢谢分享病例。

仅供参考。

Tumor in lymh node is lobular.

But p120 positive (membrane)

Not sure if they are the same areas.

these tubule structures show reduced e-cad stain

IHC 标记:

图1-5 E-cadherin

图6-8 P120

图9-10 34BE12

图8-9为淋巴结

浸润性导管癌

 TC, LCIS, and CCL in breast tissue be named ‘‘Rosen Triad,’’

（Adv Anat Pathol 2008;15:140–146)）

小管癌，小叶原位癌和柱状细胞病变，称为Rosen Triad（Rosen三征）。本例就差CCL了

赵老师说：

-小叶原位癌

-浸润性乳腺癌；标记看看到底是导管癌还是小叶癌。

 -LCIS

-invasive mammary ca; stain to see it is ductal or lobular type

浸润性小叶癌

浸润性导管癌

小叶癌化

导管原位癌

小叶原位癌

以上类型都可见到。