临床诊断：导管内乳头状瘤
图例已显示全部病变，
快速你敢诊断癌吗？因组织太小、病变少、临床没有触及明确肿物。
我没敢报，回报：疑癌变、待石蜡确诊。

最终诊断：上级医院会诊：导管内癌

 还是常规出来后在确诊吧

支持楼主的诊断，待石蜡

待石蜡吧

• The danger of frozen diagnosis for small lesion is that once the frozen is done, you will not have paraffin tissue (non-frozen) for a more definite diagnosis. I will try not to do a frozen; If we are forced to do frozen, a conservative diagnosis such as 疑癌变 is reasonable to me.
• The question is that will such a diagnosis 疑癌变 trigger a radical procedure, such as mastectomy. It will be important to know how the diagnosis affect surgeon's decision.
• For this case, I think it is micropapillary DCIS with microinvasion...Fig. 1 has too many small cluters or single cells with extension outside the confine of a lobule + ruptured mucinous cyst.
• Thanks!

 译12楼内容：

小病变冰冻诊断的危险就是 一旦做了冰冻，没有对应的石蜡组织进一步明确诊断。小病变我会尽量不做冰冻，如果必须做，保守一点的诊断如“疑癌变”更适合一些。可问题是“疑癌变”可能导致临床过度治疗，象乳腺切除，所以了解诊断对外科医生临床处理决定很重要。本例我认为是微乳头导管原位癌伴微浸。图1有一些伸展到小叶外的细胞团或单个的细胞伴破裂的粘液囊。

学习了，期待石蜡结果。

待石蜡吧