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chunhaiyao 离线
jianchixuexi 离线
lanyueliang 离线
Metastatic malignancy, unknown primary.
Agree with most. Know patient's detailed clinical history plus immunostains.
Think most common cancers in the male:
CK7, ck20, TTF-1, ER, PR, PSA, CD30
The lesion may have relation with skin in your photos.
Melanoma (s-100, melan A, HMB 45) and other skin tumors. Sorry I know very a little about skin tumors.