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B1757Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)

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楼主 发表于 2009-01-06 08:24|举报|关注(0)
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We are in 2009 already. I send this easy case for you.

Breast core biopsy:

Fig 1, 2: one area 100x, 200x

Fig 3, 4: the second area 100x, 200x

Fig 5: the third area 100x

What is your interpretation?

  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图1
    图1
  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图2
    图2
  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图3
    图3
  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图4
    图4
  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图5
    图5
标签:DCIS 乳腺浸润性导管癌
本帖最后由 于 2009-07-19 05:14:00 编辑
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41 楼    发表于2009-01-07 09:01:00举报|引用
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 i feel it has both LCIS (first several photos) and DCIS (last photo),  low nuclear grade.  Invasive cancer cannot be excluded because the first several photos show small clusters of neoplastic cells in desmoplastic-like stroma.  E-cadherin and p63 will certainly help.
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42 楼    发表于2009-01-06 23:39:00举报|引用
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 通过几例ALH/LCIS的仔细观察,发现此种病变,小叶特化间质多被纤维化所取代,并有围绕病变的趋势,不知这是不是其病变的特点?请赐教!
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广州金域病理

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43 楼    发表于2009-01-06 23:34:00举报|引用
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 Happy new year, Dr.cqzhao!  Agree with abin.

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广州金域病理

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44 楼    发表于2009-01-06 22:47:00举报|引用
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 Happy new year, Dr.cqzhao!

These pictures show LCIS or DCIS, which can be differentiated by each other for immunostaining of p120 and E-cadherin.  In the stromal pseudoinvasion is presented, and p63 immunostaining may confirm it.

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华夏病理/粉蓝医疗

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45 楼    发表于2009-01-06 10:19:00举报|引用
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 乳腺小叶原位癌。有无浸润?
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