invasive duct carcinoma? 
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- B1757Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)
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图5
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We are in 2009 already. I send this easy case for you.
Breast core biopsy:
Fig 1, 2: one area 100x, 200x
Fig 3, 4: the second area 100x, 200x
Fig 5: the third area 100x
What is your interpretation?
标签：DCIS 乳腺浸润性导管癌
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本帖最后由 于 2009-07-19 05:14:00 编辑
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×参考诊断
1. Figure5 is duct carcinoma in situ, of course. Morphology and immunostain results( smooth muscle myosin heavy chain is expressed by myoepthelial cells) support DCIS.
2. Figure 1-4 are invasive components with both p63 and smooth muscle myosin heavy chain negative
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本帖最后由 于 2009-01-24 12:20:00 编辑
P63 stains
Fig 1 first area
Fig 2 second area with SMMHC positive-looking.
Fig 3 second area. I repeat P63 stain
Now I want to see your interpretation.
I chose some cases, sent here, and tried to demonstrate some points for each case.
For this case, we are sure that invasive carcinoma is present. Now the question is if DCIS is present or all are invasive carcinoma.
You guys can think about it.
名称：图1
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本帖最后由 于 2009-01-19 12:41:00 编辑
IHC: smooth muscle myosin heavy chain
Fisrt Fig. the area for first several figs of H&E
Second Fig. the area for the last photo of H&E.
I am a little surprise to read the response. Now what is your final diagnosis for this case?
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stevenshen 离线
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Happy New Year Dr.zhao, Thank you for sharing interesting breast cases.It's very nice to learn your cases.
I think the case has both LCIS and DCIS, invasive lobular carcinoma can not be excluded. Looking forward for the your explanation and immunostaining results.
