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lfl001200546 离线
I agree with most of your opinion. It seems to me that this is a LEEP specimen given the relative abundant and intact stroma. Most parts show CIN1 (or with HPV infection in China) and few photos show CIN2 change. I am assuming that no invasive carcinoma in other parts of the specimen. Now If resection margins are negative for CIN2 lesion, then she should be able to be totally exempt from hysterectomy. Now this is a delicate issue in China since I know most of you do not use color inks to ink resection margin. You have to use your experience and judgement to evaluate if resection margins are positive or not. If margin positive for CIN2, it will be important to have an ECC to make sure CIN2 is not deep inside or involving in endocervical glands. If latter is negative, then clinicians have two options: 1) do another thin "LEEP" procedure to get rid of left over CIN2. However, in up to 80% of cases reported in US, pathologic examination cannot find any CIN2 in second LEEP specimen even previous LEEP margins are positive. 2) Most clinicians in US, at least in our hospital, will follow patient with either PAP test every 6 months and/or HPV test. Recent ALTS study indicates that HPV test in follow up is more specific since 40% of HPV positive patients will develop recurrent CIN2+ lesions when HPV is persistently positive post LEEP, compared to 5% whne HPV is negative. For this case and most cases in China, I suggest to follow with PAP plus HPV test, given no accurate position of positive margins can be provided if you do not ink the margin.
I totally agree with hpn0808's opinion that even patient asked for hysterectomy, clinicians should provide better information and advise to patient. Otherwise, what is need for doctors anyway? We doctors shoud treat patients with care and dignity in my opinion. In US, the first oath to GOD for any medical students is: NO HARM TO YOUR PATIENTS!
jiangxiaoyu 离线
liziqiang88 离线