本帖最后由 于 2007-02-05 21:20:00 编辑
This is a case of clear cell carcinoma of ovary. Many clear cell carcinomas show papillary growth; however, the cores of their often bulbous papillae are often hyalinized or myxoid rather than fibrovascular seen in papillary serous carcinoma. In addition, typical tubulocystic architecture is characteristic, which is not a characteristic of papillary serous carcinoma. Though both are grade 3 malignancies, clear cell carcinoma has a much worse prognosis (in terms of disease free survival and recurrence rate) than papillary serous carcinoma at the same stage of disease at diagnosis. Recurrence patterns of the two diseases are also different - clear cell carcinoma metastasizes to lung, bone liver in addition to lymph nodes, whereas papillary serous carcinoma mainly recur in the abdomen (peritoneal cavity) and pelvic/paraaortic lymph nodes. 这是一例卵巢透明细胞癌。许多透明细胞癌呈乳头状生长;然而,乳头轴心通常呈球茎状,且通常透明变性或粘液样变,而不是乳头状浆液性癌那样的纤维血管轴心。另外,典型的腺管状、小囊状结构也是特征性的,这也不是乳头状浆液性癌的特点。尽管都是3级恶性肿瘤,透明细胞癌比诊断时相同分期的乳头状浆液性癌的预后更差(用无病生存率和复发率衡量)。它们的复发形式也不同:透明细胞癌转移到肺、骨、肝以及淋巴结,而乳头状浆液性癌主要复发于腹部(腹腔)和盆腔/主动脉旁淋巴结(-abin译)。
This is a case of clear cell carcinoma of ovary. Many clear cell carcinomas show papillary growth; however, the cores of their often bulbous papillae are often hyalinized or myxoid rather than fibrovascular seen in papillary serous carcinoma. In addition, typical tubulocystic architecture is characteristic, which is not a characteristic of papillary serous carcinoma. Though both are grade 3 malignancies, clear cell carcinoma has a much worse prognosis (in terms of disease free survival and recurrence rate) than papillary serous carcinoma at the same stage of disease at diagnosis. Recurrence patterns of the two diseases are also different - clear cell carcinoma metastasizes to lung, bone liver in addition to lymph nodes, whereas papillary serous carcinoma mainly recur in the abdomen (peritoneal cavity) and pelvic/paraaortic lymph nodes. 这是一例卵巢透明细胞癌。许多透明细胞癌呈乳头状生长;然而,乳头轴心通常呈球茎状,且通常透明变性或粘液样变,而不是乳头状浆液性癌那样的纤维血管轴心。另外,典型的腺管状、小囊状结构也是特征性的,这也不是乳头状浆液性癌的特点。尽管都是3级恶性肿瘤,透明细胞癌比诊断时相同分期的乳头状浆液性癌的预后更差(用无病生存率和复发率衡量)。它们的复发形式也不同:透明细胞癌转移到肺、骨、肝以及淋巴结,而乳头状浆液性癌主要复发于腹部(腹腔)和盆腔/主动脉旁淋巴结(-abin译)。