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女,26岁,右乳肿块数年。
大体:最大径2.1cm乳腺组织,灰白,夹灰红小点。无牙膏状物。
全取,共4片。AB见导管内增生,CD为普通的乳腺增生症。
此为A片,免疫组化依次:SMA,p63,CK5/6,34βE12,ER,PR
(注:我们的CK5/6背景较强,染色淡黄者应视为阴性)
华夏病理/粉蓝医疗
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A) ADH
B) DCIS
B has some foci with real cribriform architecture and rigid round spaces. Cytologic atypia appears to be quite apparent to me in both A and B: large and monotonous nuclei, some appear to have nucleoli. Sorry i didn't examine the immunostained slides carefully because i was not differentiating between DCIS and invasive carcinoma.
Please note the cutoff line between UDH vs.ADH, ADH vs.DCIS is never clear and differ between pathologists.