?

Interesting but difficult case to interpret...I favor it to be non-neoplatic.  It most likely represent florid basal cell hyperplasia and extensive squamous metaplasia.  It is not typical of prostate adenocarcinoma.  Other considerations include prostatic transitional cell carcinoma with squamous differentiation or primary prostate squamous cell carcinoma, both of which are exceedingly rare. Some areas superficially resemble ductal endometriod-like prostate carcinoma, but don't think it is.  Looking forward to hear other expert's opinion and patient follow-up from the submitting pathologist if available. Thanks!

 前列腺腺癌，部分向鳞癌分化。

 同意4楼高见。不太像癌。鳞状上皮完全良性。腺上皮也还好，只是结构比较紊乱。

 有无化生性鳞癌说法？

 不太像癌,,部分向鳞癌分化

 不太像癌,,部分向鳞癌分化

 不太像癌,,部分向鳞癌分化

 似前列腺基底细胞增生伴鳞化,但要除外基底细胞癌和内翻生长型的低级别尿路上皮癌伴鳞状分化.

 Doesn't look like cancer, at least cannot diagnose based on H & E features.  Basal cell hyperplasia? Adenosis?  Transitional and squamous cell metaplasia? At least do basal cell markers and/or racemase.

 好例子 希望有最后结果

 不太像癌,,部分向鳞癌分化

 一二张有双层结构应该不是癌，后面几张应该是鳞化，因部分腺体既有前列腺腺上皮又有鳞状上皮，但有异型性，向鳞癌分化不排除，等待结果。

 学习一下！

 学习

     学习

 片子不太好!

 鳞化很显然，但看起来还是有癌变的成分。