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B241乳腺肿物--化生性癌

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楼主 发表于 2006-12-05 18:35|举报|关注(2)
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  • 乳腺肿物--化生性癌图1
    图1
  • 乳腺肿物--化生性癌图2
    图2
  • 乳腺肿物--化生性癌图3
    图3
  • 乳腺肿物--化生性癌图4
    图4
  • 乳腺肿物--化生性癌图5
    图5
  • 乳腺肿物--化生性癌图6
    图6
  • 乳腺肿物--化生性癌图7
    图7
  • 乳腺肿物--化生性癌图8
    图8
  • 乳腺肿物--化生性癌图9
    图9
  • 乳腺肿物--化生性癌图10
    图10
标签:乳腺化生性癌 vim ck
本帖最后由 于 2007-02-06 13:41:00 编辑
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金杯银杯不如人们的口杯
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1 楼    发表于2006-12-05 18:40:00举报|引用
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姓    名: ××× 性别:  女 年龄:  48
标本名称:  
简要病史:  乳腺肿物一个月.
肉眼检查:   乳腺肿物6*5*1cm1-6图.腋下淋巴结肿大5枚.7-10图

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金杯银杯不如人们的口杯

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2 楼    发表于2006-12-05 18:47:00举报|引用
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 图1-6为乳腺肿块,肿瘤细胞异型性显著,呈肉瘤样。但仍可辨认导管结构。图7-10为腋下淋巴结,导管结构更明显。

考虑乳腺浸润性导管癌(低分化癌,或间变性癌,或肉瘤样癌)伴腋下淋巴结转移。建议免疫组化检测CK、VIM确诊。

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华夏病理/粉蓝医疗

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努力让人人享有便捷准确可靠的病理诊断服务。


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3 楼    发表于2006-12-05 18:52:00举报|引用
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 乳腺肿物又重新取次材.肿物质软,有出血,境界清楚,.灰白色.
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金杯银杯不如人们的口杯

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4 楼    发表于2006-12-05 19:05:00举报|引用
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 乳腺肉瘤样癌伴腋下淋巴结转移.
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宠辱不惊,闲看庭前花开花落; 去留无意,漫随天外云卷云舒!

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5 楼    发表于2006-12-05 20:15:00举报|引用
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 乳腺多型性癌
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靠树有断,靠墙有塌,靠命有失 所以我只能自强不息!!!!!!

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6 楼    发表于2006-12-07 20:00:00举报|引用
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 重新取材乳腺肿瘤没有上皮样结构.见成熟软骨和破骨样细胞骨样基质和上图内梭形   细胞 结构                                                                                                                                                        .                                                                                                                                                                                                                                          

免疫组化:CK(pan)(-)Vimentin (+)

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              

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金杯银杯不如人们的口杯

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7 楼    发表于2006-12-07 20:18:00举报|引用
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 乳腺化生性癌有时找不到明确的癌的结构,免疫组化CK有时表达也不理想。此例淋巴结有明确的转移癌,所以还是考虑乳腺病变为化生性癌。
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the more we discuss, the more we learn from each other !!

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8 楼    发表于2006-12-07 23:12:00举报|引用
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 化生性癌。

它是指乳腺导管癌中主要成分不表现上皮和腺体而包括肉瘤样.癌可以有软骨和骨样基质和梭形细胞.

免疫组化Vimentin (+)偶而保留上皮标记.预后比导管癌更具侵袭性.

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金杯银杯不如人们的口杯

abin 离线

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9 楼    发表于2007-02-27 20:46:00举报|引用
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 又学到一例化生性癌,谢谢了!
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华夏病理/粉蓝医疗

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努力让人人享有便捷准确可靠的病理诊断服务。


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10 楼    发表于2007-05-21 12:14:00举报|引用
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 化生性癌是指瘤细胞形态与功能的变异,不仅癌实质化生,间质也化生,如浸润性导管癌间质内含软骨或骨。软骨或骨也可形成肉瘤。
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吾表兄,年四十余。始从文,连考三年而不中。遂习武,练武场上发一矢,中鼓吏,逐之出。改学医,自撰一良方,服之,卒。

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11 楼    发表于2007-05-21 12:17:00举报|引用
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 Image 1

Image 2

Image 3

The lesion has a biphasic component. In areas the lesion resembles a classic infiltrating poorly differentiated duct carcinoma with nests and cords of malignant appearing epithelial cells. Elsewhere, the lesion has a distinct chondroid appearance. The chondroid areas merge imperceptibly with the epithelial areas. The cells within the chondroid appearance have similar malignant features to that of the surrounding infiltrating carcinoma. The presence of both a malignant cartilagenous and epithelial component is diagnostic of metaplastic carcinoma. Metaplastic carcinoma is a general term for breast carcinomas in which there is an additional component other than epithelial and glandular. In this case, with both epithelial and malignant spindle cell features this lesion would be regarded as a sarcomatoid carcinoma. Some individuals make the distinction between sarcomatoid carcinoma where the epithelial and spindle cell carcinoma merges with each other in contrast to 揷arcinosarcoma?where the two components are distinct. However, there is overlap between the two both histologically and immunohistochemically, and prognostically there is no difference. Consequently, we regard both sarcomatoid carcinoma (carcinoma with spindle cell differentiation) and carcinosarcoma as the same entity.

The presence of an epithelial component typical of infiltrating duct carcinoma rules out a pure chondrosarcoma. Malignant phyllodes tumor has a malignant mesenchymal component yet the epithelium appears benign. In carcinoma with chondroid metaplasia, the cartilage would have a totally benign appearance and would not merge in with the carcinoma.

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吾表兄,年四十余。始从文,连考三年而不中。遂习武,练武场上发一矢,中鼓吏,逐之出。改学医,自撰一良方,服之,卒。

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12 楼    发表于2007-05-21 12:19:00举报|引用
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 http://pathology2.jhu.edu/sp/case.cfm?case=95&CFID=4280614&CFTOKEN=25839639

贴来给大家复习下,不知道是否只要给链结,不要复制内容,不对的地方请版主说明下。

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吾表兄,年四十余。始从文,连考三年而不中。遂习武,练武场上发一矢,中鼓吏,逐之出。改学医,自撰一良方,服之,卒。

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13 楼    发表于2008-10-14 22:23:00举报|引用
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 好病例,精彩的讲解,谢谢!
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广州金域病理
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