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wangliping 离线
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The photos show a neoplasm with features of a fibrillary astrocytoma. The spindled cells arranged in fascicles suggest meningioma, but I have not found definite meningothelial differentiation. Instead, there appears to be parenchymal infiltration (in the first 2 photos) by the neoplastic cells, which is a feature of infiltrating gliomas. Cellularity is variable and focally high, but cytologic anaplasia is not very prominent from the selected photos. At least one mitosis is depicted. Age of the patient and MRI images (tumor size, enhancement, contour) before resection are important. My differential diagnoses include WHO grade III anaplastic fibrillary astrocytoma and, less likely, WHO grade I desmoplastic cerebral astrocytoma of infancy (DCAI). More photos will definitely help me!
聞道有先後,術業有專攻
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本帖最后由 于 2008-05-21 12:45:00 编辑
The photos show a neoplasm with features of a fibrillary astrocytoma. 图片显示纤维性星形细胞瘤的特点，The spindled cells arranged in fascicles suggest meningioma, but I have not found definite meningothelial differentiation. 梭形细胞排列成束状提示为脑膜瘤的特点，但是没有发现明显的脑膜上皮分化。Instead, there appears to be parenchymal infiltration (in the first 2 photos) by the neoplastic cells, which is a feature of infiltrating gliomas. 的确，似乎有脑实质的浸润（图2）这提示为浸润性胶质瘤的特点。Cellularity is variable and focally high, but cytologic anaplasia is not very prominent from the selected photos. 从上述图片中可以看出局部细胞的密度很高，但是细胞的间变性不十分明显。At least one mitosis is depicted. 至少我看到一个分裂相。Age of the patient and MRI images (tumor size, enhancement, contour) before resection are important. 切除肿瘤之前应该考虑病人的年纪、MRI 的改变（肿瘤的大小，增强后形态），My differential diagnoses include WHO grade III anaplastic fibrillary astrocytoma and, less likely, WHO grade I desmoplastic cerebral astrocytoma of infancy (DCAI). 我的鉴别诊断包括WHO III 级的间变性纤维性星形细胞瘤 ，较少考虑第二个是儿童小脑促纤维增生性星形细胞瘤WHO I级。More photos will definitely help me!如果有更多的图片会有更大帮助。
