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女性,32岁。
临床症状及体征:发现颈部包块2年,无其它不适,月经正常,今年6月份感喉部不适,B超下发现一1×1.7×2cm包块。
大体标本检查:约2-2.5cm小枣大不整形结节一个,切面呈多结节状,主呈实性、灰白色,边缘见有淡黄色胶冻样区,约0.5cm。
binghongcha 离线
qingfengxx 离线
Tall cell variant lacks morular, cribriform and spindle cell areas. Columnar cell variant presents in older males. The encapsulated form of columnar cell variant is common in females and histologically shows greater overlap with C-MV but does not have the morules and cribriform pattern. Hyalinizing trabecular tumor shows a zellballen pattern in a hyalinized amyloid-like background. Poorly differentiated (insular) carcinoma shows areas mimicking cribriform structures but lacks morules and is associated with a higher proliferation index and necrosis.
emilypeaker 离线
这一例是非常典型的Cribriform-morular variant 甲状腺乳头状癌。免疫组化结果非常好,很好的病例。
日本内分泌病理学会都有过相关的报道。我在复习文献时,发现一例13年前的病例,电话通知临床大夫随访其消化道,未果。
另:楼主有兴趣的话,可以检测该例是否有APC基因突变。