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3 楼 发表于2011-04-22 10:48:00举报|引用
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My suggestion is that you should order CD3, CD20, Kappa, Lambda etc., to highlight the pattern and rule out plasma cell disease. The differential diagnosis I think should include marginal zone lymphoma, Lymphoplasmacytic lymphoma, less likely Sj246;gren’s syndrome or other reactive condition. It really looks like a low grade B-cell lymphoma. If immunostain is not that much helpful, you should do IgH gene arrangement to confirm.
Hope it is helpful.
My suggestion is that you should order CD3, CD20, Kappa, Lambda etc., to highlight the pattern and rule out plasma cell disease. The differential diagnosis I think should include marginal zone lymphoma, Lymphoplasmacytic lymphoma, less likely Sj246;gren’s syndrome or other reactive condition. It really looks like a low grade B-cell lymphoma. If immunostain is not that much helpful, you should do IgH gene arrangement to confirm.
Hope it is helpful.
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