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读片会讨论意见
A:1.化生性癌;2.排除肉瘤
B:伴异源性成分的化生性癌
C:(右乳)化生性癌。
D:考虑:①梭形细胞癌②骨肉瘤
E:恶性纤维组织细胞瘤,局部骨化,待标记与间叶化生性癌鉴别。
F: Well demarcated spindle cell lesion with osteo differentiation,
differential includes
- Metaplastic carcinoma, if there is CK positivity
- Phyllodes tumors, sample more tissue and looking to benign epithelium components
G: osteogenic sarcoma, most likely associated with malignant
phyllodes tumor or PT recurrence, primary extraskeletal OS involving breast is less likey. Clinical
correlation is recommended.
H:1 骨肉瘤,2化生型癌伴骨肉瘤, 3恶性分叶状肿瘤间质骨肉瘤分化(异
源性成分)
I:1.化生性癌;2.排恶性叶状肿瘤;
J:右侧乳腺骨肉瘤,需IHC,排除化生性癌。
免疫组化结果:ER(-)、PR(-)、HER2(-)、CK(-)
原单位意见:诊断为化生性癌。但多次取材后未见明确上皮,不除外原发骨肉瘤。
讨论:乳腺骨肉瘤占全部乳腺肉瘤的12%,纯粹的骨肉瘤必须与起源于叶状肿瘤或化生癌
肉瘤的骨肉瘤鉴别。
华夏病理/粉蓝医疗
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努力让人人享有便捷准确可靠的病理诊断服务。