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1 楼 发表于2007-11-23 14:59:00举报|引用
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Though the vasculature, architecture and cytology mimic that of a hemangiopericytoma and a glomangioma, the formation of scattere round glandular spaces and the anatomic location of the lesion are much more consistent with a myoepithelial neoplasm of salivary gland origin. Immunohistochemical stains (smooth muscle-specific actin, calponin, S100, CD34, GFAP) and reticulin silver stain may help its confirmation. The tumor is quite cellular, but no apparent mititic figures, necrosis or anaplastic features are apparent on the available photos. This may be a cellular pleomorphic adenoma or monomorphic adenoma depending on the amount of characteristic myxoid stroma. The possibility of myoepithelial carcinoma is relatively low. Since the tissue received is disrupted without apparent capsule, re-excision is needed.
Though the vasculature, architecture and cytology mimic that of a hemangiopericytoma and a glomangioma, the formation of scattere round glandular spaces and the anatomic location of the lesion are much more consistent with a myoepithelial neoplasm of salivary gland origin. Immunohistochemical stains (smooth muscle-specific actin, calponin, S100, CD34, GFAP) and reticulin silver stain may help its confirmation. The tumor is quite cellular, but no apparent mititic figures, necrosis or anaplastic features are apparent on the available photos. This may be a cellular pleomorphic adenoma or monomorphic adenoma depending on the amount of characteristic myxoid stroma. The possibility of myoepithelial carcinoma is relatively low. Since the tissue received is disrupted without apparent capsule, re-excision is needed.
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