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- 这个宫颈癌患者的卵巢，里面有甲状腺组织，是异位？
--------- Strumal carcinoid
1. Ovarian tumor contains both carcinoid and thyroid tissue.
2. The tumors can be in pure form with only carcinoid and thyroid components or associated with dermoid cysts.
3. The tumors are almost always clinically benign.
4. The two components may be contiguous or intimately admixed (more often).
5. Stains: TTF-1 for thyroid component and chromogranin or synaptophysin for carcinoid component.
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本帖最后由 于 2010-09-13 01:53:00 编辑
More terminology issues for new pathologists
--------Primary ovarian carcinoid:
1 second most common monodermal teratoma
2. Present in pure form (15%) and with other teratomatous elements (85%)
3. May occur at any age, but most patients are peri- or postmenopausal women with nonspecific symptoms.
4. Carcinoid syndrom may occur in some patients
5. Growth patters includ insular, trabecular, mixed, and mucinous types, just as carcinoids of the GI tracts.
6. Specific and sensitive marker is chromoganin. Synatophysin is fine also.
7. Always consider to rule out GI metastatic carcinoid. The prognosis is different. Clinical history, tumor components, size, location may help you. If patients have the history of GI carcinoid, the chance of metastasis is high. If ovarian carcinoid tumor with other teratomatous elements, the possibility of ovarian primary is high.Pathologists do not need to mention definitely it is primary or second carcinoid in the report even though you can say "favor for...."
8. My personal experience is that CDX2 stain may have some value to distinguish ovarian carcinoid from GI ones. Most GI carcinoids (especially upper GI, appendix) are positive for CDX2 in the literatures. My current study shows that almost all the ovarian carcinoids are negative for CDX2.
| 以下是引用viivi薇在2010-9-12 11:38:00的发言：
Dr.zhao,you are favor mature cystic teratoma about the case,right? thank for your reference |
If the tumor contains only thyroid tissue, we should call 卵巢甲状腺肿.
If the tumor contains thyroid tissue and other benign components, we can call mature cystic teratoma with thyroid component.
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本帖最后由 于 2010-09-13 01:07:00 编辑
| 以下是引用cqzhao在2010-9-12 5:29:00的发言：
Terminology: ----Struma ovarii: 卵巢甲状腺肿: teratoma composed either exclusively or predominently of thyroid tissue. 1. Most common monodermal teratoma 2. 2-3% of all ovarian teratoma 3. Most patients in their fifth decade 4. May have hyperthyroidism 5. Malignancy is rare, but can have, especially papillary ca. ----About 20% mature cystic teratoma (dermoid cyst) may have thyroid tissue. They are not called struma ovarii if they contain many other components. |
专业术语
----卵巢甲状腺肿：畸胎瘤的组成中甲状腺组织不是唯一的就是主要的构成成分
1.最常见的单胚层畸胎瘤
2.2-3%的卵巢畸胎瘤
3.绝大多数的病人发病年龄是在50岁左右
4.可患有甲亢
5.恶性肿瘤比较罕见，但是也可能发生，尤其是乳头状癌
---大约20%成熟的囊性畸胎瘤（皮样囊肿）中含有甲状腺组织，但是如果畸胎瘤中包含了其他的组成成分，它们不能被称做卵巢甲状腺肿。
- there is no reason not to follow ur heart
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本帖最后由 于 2010-09-13 01:04:00 编辑
| 以下是引用response3在2010-9-12 12:25:00的发言：
小弟才疏学浅的翻译，希望大家指正（英文4级没过，斗胆翻译，希望不要拍砖啊@@） 术语： |
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本帖最后由 于 2010-09-13 01:02:00 编辑
| 以下是引用cqzhao在2010-9-12 5:29:00的发言：
Terminology: ----Struma ovarii: 卵巢甲状腺肿: teratoma composed either exclusively or predominently of thyroid tissue. 1. Most common monodermal teratoma 2. 2-3% of all ovarian teratoma 3. Most patients in their fifth decade 4. May have hyperthyroidism 5. Malignancy is rare, but can have, especially papillary ca. ----About 20% mature cystic teratoma (dermoid cyst) may have thyroid tissue. They are not called struma ovarii if they contain many other components. |
小弟才疏学浅的翻译，希望大家指正（英文4级没过，斗胆翻译，希望不要拍砖啊@@）
术语：
----卵巢甲状腺肿：全部或者大部分是甲状腺组织组成的畸胎瘤
1。最常见的单胚层性畸胎瘤
2。 2-3％含有卵巢畸胎瘤
3。大部分患者发生在50岁
4。可能有甲状腺功能亢进症
5。恶性肿瘤罕见，但可以有，尤其是乳头状的癌。
----约20％成熟性囊性畸胎瘤（皮样囊肿）可能甲状腺组织。如果它们包含许多其他成分，那么他们不是所谓的卵巢甲状腺肿。
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本帖最后由 于 2010-09-13 01:11:00 编辑
| 以下是引用cqzhao在2010-9-12 5:29:00的发言：
Terminology: ----Struma ovarii: 卵巢甲状腺肿: teratoma composed either exclusively or predominently of thyroid tissue. 1. Most common monodermal teratoma 2. 2-3% of all ovarian teratoma 3. Most patients in their fifth decade 4. May have hyperthyroidism 5. Malignancy is rare, but can have, especially papillary ca. ----About 20% mature cystic teratoma (dermoid cyst) may have tyroid tissue. They are not called struma ovarii if they contain many other components. |
Dr.zhao,you are favor mature cystic teratoma about the case,right?
thank for your reference
- there is no reason not to follow ur heart
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本帖最后由 于 2010-09-13 01:02:00 编辑
Terminology:
----Struma ovarii: 卵巢甲状腺肿: teratoma composed either exclusively or predominently of thyroid tissue.
1. Most common monodermal teratoma
2. 2-3% of all ovarian teratoma
3. Most patients in their fifth decade
4. May have hyperthyroidism
5. Malignancy is rare, but can have, especially papillary ca.
----About 20% mature cystic teratoma (dermoid cyst) may have thyroid tissue. They are not called struma ovarii if they contain many other components.
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