Peripheral T-Cell lymphoma, Lymphoepithelioid Variant
(Lennert Lymphoma) |
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Micro:
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Often diffusely replaces the lymph node architecture
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Numerous epithelioid histiocytes in small clusters or linear rows
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The neoplastic T-cells are small without significant atypia
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IPX: tumor cells usually CD8+
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DDX:
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Sinusoidal histiocytosis: well-preserved architecture of lymph node with expansion of sinus
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Sarcoidosis: well-formed, non-caseating granuloma, the remaining lymph node architectures is preserved |
Reference: |
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Ioachim's Lymph Node Pathology, 4th edition
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WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues, Fourth Edition. 2008. |