| 图片： | |
|---|---|
| 名称： | |
| 描述： | |
- 87 y/o with increased PSA and pancytopenia
图1
图2
图3
图4
图5
图6
图7
祝贺第一届华夏病理学术论坛会议召开 ！！！
Clinical History.87 y/o male with:
Hematuria
PSA 19.4
Papillary transitional cell carcinoma
Bone marrow biopsy for pancytopenia
WBC:5.8, Hgb:8.5, Hct:28.9, plt:36
Peripheral smear showed 4% blasts
#1, Peripheral blood, #2-6, Bone marrow aspirate, #7-8, Bone marrow biopsy
标签：
×参考诊断
-
This is a case of acute erythroleukemia, AML-M6.
From the microphotos, particularly #2 and #3, we can see several large atypical neoplastic cells with basophilic granular cytoplasm and large multiple prominent nucleoli. Picture #6 shows a large megaloblastoid erythroid precursor, evidence of dysplasia, although the picture is less optimal. The section shows sheet of these large cells seen on the aspirate, which is very evenly distributed. This is also a good indication of a marrow disease rather than a metastatic disease。 Patient had increased PSA, but prostate carcinoma will not have the basophilic granular cytoplasm and bi-nucleated cells.
PAS stain showed block type positivity in the blasts.
