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病史摘要:
女性患者王X 30岁
主诉:无意间发现右侧乳晕下一包块.
外科情况:右侧乳晕下可扪及一3.0X3.0大小的包块,边界清,活动度尚好。
B超:发现右侧乳晕下可见一29mmX28mm液性暗区,边界清晰。
临床诊断:右侧乳腺囊肿
常规消毒下行细针吸取穿刺,抽吸出约7毫升淡咖啡色液体。全部离心,取试管底部沉淀物常规涂片、制片。HEX5
乳腺导管乳头状瘤细胞学图像
Figure 1 :FNA smears show uniform cells with abundant cytoplasm, eccentric nuclei and inconspicuous nucleoli lying in groups and sheets. Apocrine metaplasia is also seen in some areas. (Leishman-Giemsa, x 400)
(From PathologyOutlines.com)
Highly complex papillary apocrine change, low power.
Even at low power, the low nuclear to cytoplasmic ratio is readily apparent along with the uniform cell size and hints of decapitation secretions. The vacuolated cytoplasm and decapitation secretions along with the bland nuclear features are characteristic.
GO ON.
Breast-nonmalignant
Fibrocystic disease
Apocrine metaplasia of breast
Digital Atlas of Breast Pathology by Meenakshi Singh, MD © - Department of Pathology, Stony Brook University Medical Center.
Highly complex papillary apocrine change, high power.
(From PathologyOutlines.com)
cqzhao 老师会诊意见:(ZT)
Interesting case and thank for sharing.
I once did a lot of breast FNA when I was cytofellow at USC where all breast mass lesions would be referred to cytopathologists to do FNA. Now days FNA is rare to be used for the primary evaluation of breast lesions at Magee and most large medical centers in the US. If we do not consider the money, cost-effect, it will be easy for pathologists to read breast core bx than FNA.
For this case I woud like to sign out:
-Negative for maligancy.
-clusters of apocrine cells.
-Suggestive of fibrocystic changes.
Comment:
Mostly it is a lesion with cystic papillary apocrine metaplasia even though the papillary lesion cannot be completely excluded.
FNA combined with clinical impression and imaging finding (Triple test) is highly accurate. If one of the parameters is discordant, surgical biopsy is warranted. Benign Triple test should return for follow up in 3 to 6 months. (write this part in your comment for all FNA breast cases to protect yourself).
In fact 3 cm cystic lesion should be excisioned. Of cause I will not write this sentence in my report. Pathologists do not need to take all the responsblity for patient care. We take care of the part we should have.
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