肉眼所见：十二指肠球部烧瓶型溃疡，粘膜桥形成。

镜下观察：溃疡改变，全层炎症，多量嗜酸粒细胞，平滑肌溶解样改变，肉芽肿性炎，较多神经节样细胞，请各位专家帮助鉴别一下是否为阿米巴滋养体？

 谢谢各位老师的指导。

因为我感觉网上提供的照片，还是太局限，对于本病例、我感觉用普通的消化道溃疡，又不能解释，所以我今天带切片去瑞金医院金老师那里，金老师帮我看了，我感觉本病例诊断问题应该是解决了。（在此也感谢金老师）。十二指肠在错构的基础上合并溃疡。稍后我在提供更多的照片，与大家分享，谢谢。

这些是神经节细胞(Ganglion cells)

It does not look like a biopsy specimen. If this is a resection specimen, more sections/blocks need to be examined.

Please show us some photos of the mucosal surface, and interface of inflamed area and non-inflamed area.

Based on the information provided, the pathological changes are not specific. I agree that Crohn's disease should be in the differential diangosis. Certainly, we need to carefully look for parasites due to the marked eosinophils. Is any elevated eosinophils in the peripheral blood test?

 节细胞。神经增生常出现于Crohn，但非其特有。

请显示肉芽肿的形态和全层炎症浸润的形态。

需要找有无裂隙样溃疡、边界清楚的非坏死性小肉芽肿、全层聚集灶性分布的慢性炎症细胞浸润。