学习！

 

 哦，还真没有详细问过，明天去问组织学医生，回来答复你啊呵呵。

 小荷,可能我问的问题低级了点,你的组织学诊断是鳞癌的脑转移么?

 

 明天上传组织学给大家.

 再做个巴氏染色看看协助判断角化也不知可行与否。试试？

好主意.

 楼上的回复太精彩了！！！

细胞变性显而易见，又是囊性的，我猜测是病灶的变性坏死。单就细胞形态而论，不能除外鳞癌。这种情形之下，试染IHC也许有意义；再做个巴氏染色看看协助判断角化也不知可行与否。试试？

 试译mjma老师的发言：

       图片中瘤细胞丰富、异型、多形，足以诊断恶性。但是，高倍镜下这些瘤细胞明显变性，可能是转移性的(肉瘤、肉瘤样癌、鳞癌)或原发的（胶质母细胞瘤）。我会查看患者MRI情况，首先排除胶质母细胞瘤。因为一些不清楚的原因，鳞癌（从肺或其它部位）转移到脑相当罕见。

The photos are hypercellular, and cells are atypical and pleomorphic enough for a malignancy. However, they are all degenerated on high power views and could represent any of several possibilities - both metastatic (sarcoma, sarcomatoid carcinoma, squamous cell carcinoma) and primary (glioblastoma). I would carefully review the MRI and vigorously rule out glioblastoma first. For some unclear reason, metastatic squamous cell carcinoma (from lung or elsewhere) to the brain is quite rare.

考虑:肺的磷癌,颅内转移

 恶性，符合鳞癌转移

 鳞癌吧？转移的？