鳞癌吧？转移的？

 恶性，符合鳞癌转移

考虑:肺的磷癌,颅内转移

The photos are hypercellular, and cells are atypical and pleomorphic enough for a malignancy. However, they are all degenerated on high power views and could represent any of several possibilities - both metastatic (sarcoma, sarcomatoid carcinoma, squamous cell carcinoma) and primary (glioblastoma). I would carefully review the MRI and vigorously rule out glioblastoma first. For some unclear reason, metastatic squamous cell carcinoma (from lung or elsewhere) to the brain is quite rare.

 试译mjma老师的发言：

       图片中瘤细胞丰富、异型、多形，足以诊断恶性。但是，高倍镜下这些瘤细胞明显变性，可能是转移性的(肉瘤、肉瘤样癌、鳞癌)或原发的（胶质母细胞瘤）。我会查看患者MRI情况，首先排除胶质母细胞瘤。因为一些不清楚的原因，鳞癌（从肺或其它部位）转移到脑相当罕见。

 楼上的回复太精彩了！！！

细胞变性显而易见，又是囊性的，我猜测是病灶的变性坏死。单就细胞形态而论，不能除外鳞癌。这种情形之下，试染IHC也许有意义；再做个巴氏染色看看协助判断角化也不知可行与否。试试？

 再做个巴氏染色看看协助判断角化也不知可行与否。试试？

好主意.

 明天上传组织学给大家.

 

 小荷,可能我问的问题低级了点,你的组织学诊断是鳞癌的脑转移么?

 哦，还真没有详细问过，明天去问组织学医生，回来答复你啊呵呵。

 

 学习！