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liguoxia71 离线
以下是引用XLJin8在2010-4-22 17:29:00的发言:
您的诊断: 1)慢性炎症? 2)低分化腺癌? 3)NK/T细胞淋巴瘤? 4)Wegerner 肉芽肿? 5)其他? |
Good differential diagnosis. The major feature is necrotizing granuloma with mixed inflammatory cells. By histology alone, I will favor a non-neoplastic process. However, if I have only one antibody, I will do CK. Clinical correlation is important, looking for lymphocytosis, anti-nuclear antibodies, among others.
很好的鉴别诊诊断。图像中的主要特征是混有炎细胞的坏死性肉芽肿。单从组织学考虑,我倾向于非肿瘤性的病变。我认为做个CK是必要的。与临床指标的相关性很重要,可以查一下淋巴细胞增多的程度、抗核抗体等指标。
(薄冰之旅试译)
以下是引用谈东风在2010-4-23 5:30:00的发言:
支持谈东风教授的意见,虽然会诊结果是NK/T,但看起来有不象的地方,最后有几幅图是肉芽肿样炎症改变,这在NK/T很少见,NK/T的坏死都是弥漫的碎片样的嗜碱性坏死,还有细胞的异形性也不是特别明显,缺乏大\中\小细胞混杂,也未见到侵血管现象,也许只有免疫组化支持才诊断的吧. Good differential diagnosis. The major feature is necrotizing granuloma with mixed inflammatory cells. By histology alone, I will favor a non-neoplastic process. However, if I have only one antibody, I will do CK. Clinical correlation is important, looking for lymphocytosis, anti-nuclear antibodies, among others. |