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- 请教一个关于宫颈活检上皮内空泡细胞的问题
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HPV infection/CIN is a newer concept in China. I remember when i was in CHina in late 80's early 90's, nobody knew much about it. so, I suggest you don't trust your EXPERIENCED teacher too much. You need to open a good book and read about HPV infection/cervical dysplasia and go to meeting or listen to on-line talk.
You mean 70% cervical biopsies for abnormal pap smears? Depending on how good your pap smear reports are. Our cervical biopsies are almost all for abnormal pap smears (ASCUS with positive high risk HPV, LSIL or HSIL), so the vast majority of our cervical biopsies have >HPV/CIN 1 lesions.
5% HPV effects is too low. Either your teacher missed many HPV/CIN1, or your cytopathologists are too bad, overcalled pap smears.
But, cells with halo don't mean they are HPV infected cells. Inflammation, older ladies with glyconenation, fixation artifact, young pregnant women can all have cells with halo. In contrary, some HPV/CIN1 don't have koilocytes. It is the nuclear features that determine the diagnosis.
Condyloma is caused by HPV infection, but most time by low risk HPV infection, and you see koilocytes in condyloma too.
