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- 肠系膜淋巴结（会1339）-FDC
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panzenggang 离线
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本帖最后由 于 2008-04-12 14:55:00 编辑
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CD21: CR2-complement component (3d) receptor 2, and EBV receptor;
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CD23: IgE Fc receptor, FcεRII;
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CD35: erythrocyte complement receptor 1 (CR1, also known as C3b/C4b receptor and immune adherence receptor)
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Clusterin: designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP-40 and testosterone-repressed prostate message 2 (TRPM2). A marker of ALCL.
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Am J Clin Pathol. 2007 Nov;128(5):776-82.
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Am. J. Hematol. 82:924?28, 2007
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USCAP, Denver, 2008. Abstract 1169 and 1175
Follicular dendritic cell sarcoma vs. Interdigitating dendritic cell sarcoma
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Follicular dendritic cell sarcoma |
Interdigitating dendritic cell sarcoma |
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Location of Normal Counterpart |
Germinal Center |
T cell areas (paracortex and interfollicular areas of lymph node, splenic periarteriolar lymphoid sheaths) |
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Origin |
Mesenchymal |
the monocyte-macrophage lineage |
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Electron microscopy |
Numerous long, slender cytoplasmic processes connected by desmosomes |
Complex interdigitating cellular junctions |
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CD21 |
+ |
- |
| CD35 | + | - |
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S100 |
- |
+ |
| CD23 | + | - |
| Clusterin | + | - |
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CD1a |
- |
- |
| HMB-45 | - | - |
| CD3 | - | - |
| CD20 | - | - |
| CD45 | - | +/- |
| CD68 | - | - |
| Lysozyme | - | - |
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Reference | |
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| Summarized by Zenggang Pan, MD, PhD | |
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zhongshihua 离线
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