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Omental masses(网膜肿块)

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楼主 发表于 2009-10-08 02:14|举报|关注(0)
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姓    名: ××× 性别:  female(女) 年龄:  66
标本名称:  Omental biopsy(网膜活检)
简要病史:  
肉眼检查:  

 

This is a 66-year-old lady with multiple omental masses. The gynecologist wants to know if this is a tumor of the GYN tract? What's your differential diagnosis?

(66岁女性,多发性网膜肿块。妇科要求知道这是否是女性生殖道肿瘤?你的鉴别诊断?__abin译)

  • Omental masses(网膜肿块)图1
    图1
  • Omental masses(网膜肿块)图2
    图2
  • Omental masses(网膜肿块)图3
    图3
  • Omental masses(网膜肿块)图4
    图4
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本帖最后由 于 2011-03-11 10:03:00 编辑
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1 楼    发表于2009-10-20 21:05:00举报|引用
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本帖最后由 于 2009-10-21 21:17:00 编辑

 谢谢大家的讨论。Abin, you are the first one to raise the possibility of GIST from the extra-gastrointestinal tract, job well-done! 96298: you posted the exact abstract that I would like to post also, which is an excellent paper on omental GIST. Thank you!

This is a case of extra-gastrointestinal GISTs presented as omental masses (NOT endometrial mass). Yes, I did CD34 and it is focally positive, not as strong as CD117. Now, this case was sent to an outside institution for mutational analysis as suggested by the above paper. This is the second case I had this year of an omental GIST, just like to share with you

(大致翻译:

abin第一个提出胃肠道外GIST的可能性。96298提供了准确的文献摘要,这也是我想做的,这是一篇关于网膜GIST的好文献。谢谢你们!

这是一例胃肠道外GIST,表现为网膜肿块(不是内膜肿块)。CD34局灶阳性,没有CD117表达那么强。现在本例送往院外研究机构做突变分析,如文献所建议。这是今年我遇到的第二例网膜GIST,很高兴与大家分享。

abin译)

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2 楼    发表于2009-10-19 23:24:00举报|引用
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本帖最后由 于 2009-10-21 21:09:00 编辑

 I also did the following immunos: CD10 negative, HMB45 negative, Inhibin negative, synaptophysin and chromogranin negative. The only stain that is strongly positive is CD117 (c-kit). Any thoughts?

(我也做了以下免疫组化:CD10-,HMB45-,Inhibin-,Syn-,CgA-。仅CD117 (c-kit)强阳性。有何考虑?__abin译)

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3 楼    发表于2009-10-17 03:51:00举报|引用
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本帖最后由 于 2009-10-21 21:07:00 编辑

 Thank you abin for the translation and discussion. I did all the cytokins and mesothelial markers (AE1/AE3, CK7, Cam5.2, EMA, CK5/6, Calretinin, and WT-1), they are all negative. What should I do?

(谢谢abin翻译并讨论。我做了CK和间皮标记物(AE1/AE3, CK7, Cam5.2, EMA, CK5/6, Calretinin, and WT-1),它们全部阴性。下一步我该怎么办?__abin译)

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