膀胱可以发生鳞状细胞癌的，但需与尿路上皮癌伴鳞化区别。

 浸润性尿路上皮癌。

 浸润性高级别尿路上皮癌伴鳞癌分化

    浸润性高级别尿路上皮癌伴鳞癌分化

 请问各位老师：报浸润性尿路上皮癌？还是浸润性尿路上皮癌伴鳞化？鳞癌成分占多少才报呢？

 I favor 报浸润性尿路上皮癌. 尿路上皮癌伴鳞化 has to show 1) keratin-pearl formation, and/or 2) intercellualr bridges, and/or 3) keratotic cellular debris.  If there is squamous differentiation (even it is very little), my report will be worded as "urothelial carcinoma, high grade, with squamous differentiation (x%).

 浸润性尿路上皮癌，不太考虑鳞癌。

  浸润性尿路上皮癌，不太考虑鳞癌。

 invasive high grade urothelial carcinoma

Clear-cut squamous differentiation is not seen here.

I am more generous to report squamous differentiation...There is clearly threshold and individual experience. I would report invasive urothelial carcinoma with squamous differentiation.  The argument to report "squamous" (if it is true) is to provide useful information when evaluating of any nodal and distant metastasis.