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- 求助侵袭性葡萄胎免疫组化项目??
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Invasive molar pregnancy is extremely rare, but is one of te pre-cancer stage for choriocarcinoma. Although several immunohistochemical biomarkers/antibodies have been studied in invasive mole, such as loss of E-cadherin, high labeling of Ki67 and expression of p53, so far these are still experimental studies and not applied to diagnosis. Therefore, no "magic bullets" yis available for us et, the diagnosis is still mostly relied on H&E morphology. ....................................................................................................................................................................................................................
- 不坠青云之志，长怀赤子之心
What is your differential diagnoses before you apply immunohistochemistry? Immunostains can mislead you if you do not have specific selection. I just have a consultation case sent to me from a hospital in Seattle. A simple cervical biopsy which can be done by maxium three stains. They have done104 immunostained slides, but still do not know what it is since they were trapped in IHC interpretation puzzle. At the end, H&E morphology prevails. Please specify what kind of case you have and what are your differential diagnoses.
- 不坠青云之志，长怀赤子之心
