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About 70 y/f with breast lesion.
Noticed that 197 used the words "传说".I paste here another case for your guys. Do not say 传说 in future.
angisarcomas are the most frequent primary sarcoma of the breast, but they are still uncommon. They may arise spontaneously or following radiation therapy or following radial mastectomy as the result of chronic lymphedema.
Breast angoiosarcomas include those involve skin (cutaneous), breast parenchyma or both. They share similar prognosis. Also breast argiosarcoma 肿瘤总体看来同发生于皮肤和软组织的血管肉瘤有类似的临床过程 (see above paper).
Generally angiosarcomas show ill-defined lesions that contain cullular areas with atypia, mitotic activity, and necrosis. Often some features may be more obvious in some cases than that in other cases.
High grade angiosarcomas often contain low or intermediate angiosarcoma component (see the photos of this case).
Anyway for above case: solid areas spindle cells, marked cytologic atypia, mitosis, necrosis. It is a typical high grade angiosarcoma.
以下是引用wq_9603在2009-7-7 7:57:00的发言:
根据各位老师的意见 以后类似的病例干脆写:(乳腺)血管肉瘤。 |
You are right.
The report will include
Angiosarcoma, grade, size, margin et al.
I do not think we need to distinguish the origins; breast cutaneous vs. paranchyma. At least we do not do it.
乳腺血管肉瘤的组织学特征(from Rosen Breast Pathology)
组织学特征 低级别 中级别 高级别
病变累及乳腺实质 有 有 有
吻合的血管腔 有 有 有
深染的内皮细胞 有 有 有
内皮细胞成簇 极少 有 显著
乳头形成 无 局灶 有
实性和梭形细胞灶 无 无或极少 有
核分裂 罕见或无 见于乳头区 多;低级别区域也有
血湖 无 无 有
坏死 无 无 有
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对照上表,本例有:坏死,血湖,核分裂(非常多),实性区和梭形灶,内皮簇……应该归入高级别血管肉瘤。
华夏病理/粉蓝医疗
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