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Thank abin to send the table above.
We can find a lot of tables from different expert text book. In practice low grade tumor needs to differ from benign or atypical hemagioma. Low grade tumor is easy to distinguish from intermediate or high grade tumor. However it is difficult to tell the difference between the intermediate grade tumor and high grade tumor for some cases. Fortunately it is not clinical important to distinguish intermediate grade tumor from high grade tumor.
Thank Dr. Zhang, thank you for your input.
Dr. Rosen's paper indicated that ki67 may be useful in distinguish low grade angiosarcoma from benign hemagioma. Last week I asked the question to Dr. Christopher Fletcher, Professor and Director of Surgical Pathology, Brigham & Women's Hospital, Harvard medical School. He answered that We do not use Ki-67 in this context.
Anyway ki67 stain is not useful for dx of high grade or intermediate grade angiosarcoma.