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女,72岁,右乳肿块,径1.5cm。
Irregular shaped tubules (seem no myoepithelial surrounding) within dense stroma: Invasive tubular carcinoma.
I always do myoepithelial marker stain in clinic if I am not 100% sure.
Cut-off to dx of pure tubular ca: 75% vs. 90% of tubular structure. In fact we use 100% strict rule now. Otherwise we call inv ductal ca with tubular feature, then give about xx% tubular structure in comment.
(悠远译):不规则的尖锐小管(看上去没有肌上皮围绕)伴有致密的间质:浸润性小管癌。
在临床上如果不是100%确定我一定会做肌上皮标记。
定义单纯性小管癌,标准为小管结构达75%或90%。事实上我们现在使用达100%小管结构的严格标准,否则我们诊断为浸润性导管癌伴有小管特征,然后注明小管结构所占的比例。
wangxuanju 离线