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I think WHO grade I dysembryoplastic neuroepithelial tumor (DNT) is the most likely diagnosis, but one would like to see isolated floating neurons in the microcysts in addition to the small oligodendrocyte-like cells and neuropil-like fibrillary matrix. A differential diagnosis is pilocytic astrocytoma, which could look like oligodendroglioma focally. However, I do not see the characteristic features of pilocytic astrocytoma - biphasic growth pattern, microcysts, Rosenthal fibers, and eosinophilic granular bodies. I don't think this is a case of ependymoma or subependymoma or oligodendroglioma.
liguoxia71译;
我考虑可能是WHOI级的DNT(胚胎发育障碍的神经上皮肿瘤)。但DNT中除了少突胶质细胞样的小细胞和神经毡样胶质纤维基质外,还应该见到微囊中漂浮的神经元。鉴别诊断是毛细胞型星形细胞瘤,它可以局灶呈少突胶质细胞瘤样。但我并没见到毛细胞型星形细胞瘤典型特征:双极生长方式、微囊、Rosenthal纤维和嗜酸性颗粒小体。不考虑室管膜瘤、室管膜下瘤或少突胶质细胞瘤。
聞道有先後,術業有專攻