Good morning, my colleagues:

This is an interesting case of breast lesion.  I would like to share with you for educational purpose.  My fellow and I will publish a short review of this entity in the future issue of Archives of Pathology and Laboratory Medicine. 

This is a 54-year-old female with history of breast nodule measuring 2.5 x 2 x 1.8 cm.  Skin over the nodule shows crusting and ulceration.  Mammography demonstrates a mass in the subareolar region with dense and irregular outline, spicular formation and foci of microcalcifications. Ultrasonography shows an ill-defined mass with heterogeneous internal echoes. Radiographic findings suggest malignancy.

 谢谢，非常好的病例，再次学习并同意“乳头的汗管瘤样腺瘤syringomatous adenoma of the nipple”，同义词“浸润性汗管瘤样腺瘤infiltrating syringomatous adenoma”。

鉴别诊断包括：

浸润癌（小管癌和低度恶性腺鳞癌）、乳头部腺瘤or旺炽性乳头状瘤病、乳头状汗管囊腺瘤syringocystadenoma papilliferum

    You are all very good.  What is the differential diagnosis?

 Syringomatous adenoma of the nipple

同意。

 翻译楼上：

我考虑乳头汗管瘤样腺瘤。如果错了给我纠正。谢谢分享这一有趣病例！期待最后结果。

 I think it is a Syringomatous adenoma of the nipple. Correct me if I am wrong.

Thank for sharing the interesting case.

Waiting for your final dx.

 谢谢Dr.quanxun

我也考虑乳头部腺瘤。

Good morning, my colleagues:

This is an interesting case of breast lesion.  I would like to share with you for educational purpose.  My fellow and I will publish a short review of this entity in the future issue of Archives of Pathology and Laboratory Medicine. 

This is a 54-year-old female with history of breast nodule measuring 2.5 x 2 x 1.8 cm.  Skin over the nodule shows crusting and ulceration.  Mammography demonstrates a mass in the subareolar region with dense and irregular outline, spicular formation and foci of microcalcifications. Ultrasonography shows an ill-defined mass with heterogeneous internal echoes. Radiographic findings suggest malignancy.

名位同行，早上好：

   这是一例有趣的乳腺病例，做为教学目的我想与你们分享这一病例。我与我的进修生将在下一期Archives of Pathology and Laboratory Medicine杂志上发表一篇这种病变的短的回顾性研究。

    这是一个54岁的女性，乳腺有一2.5*2*1.8cm肿块。肿块表面皮肤溃疡、结痂。乳房影像学显示在乳晕下区域有一边界不规则的高密度肿块，毛刺状外形，灶性微钙化。超声检查显示一内部回声不均质的界限不清楚的肿块。放射学结果考虑恶性肿瘤。

搬个马扎学习......

形态符合乳头腺瘤