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We are in 2009 already. I send this easy case for you.
Breast core biopsy:
Fig 1, 2: one area 100x, 200x
Fig 3, 4: the second area 100x, 200x
Fig 5: the third area 100x
What is your interpretation?
Happy new year, Dr.cqzhao!
These pictures show LCIS or DCIS, which can be differentiated by each other for immunostaining of p120 and E-cadherin. In the stromal pseudoinvasion is presented, and p63 immunostaining may confirm it.
华夏病理/粉蓝医疗
为基层医院病理科提供全面解决方案,
努力让人人享有便捷准确可靠的病理诊断服务。
I think the case has both LCIS and DCIS, invasive lobular carcinoma can not be excluded. Looking forward for the your explanation and immunostaining results.
stevenshen 离线
IHC: smooth muscle myosin heavy chain
Fisrt Fig. the area for first several figs of H&E
Second Fig. the area for the last photo of H&E.
I am a little surprise to read the response. Now what is your final diagnosis for this case?
P63 stains
Fig 1 first area
Fig 2 second area with SMMHC positive-looking.
Fig 3 second area. I repeat P63 stain
Now I want to see your interpretation.
I chose some cases, sent here, and tried to demonstrate some points for each case.
For this case, we are sure that invasive carcinoma is present. Now the question is if DCIS is present or all are invasive carcinoma.
You guys can think about it.