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We are in 2009 already. I send this easy case for you.
Breast core biopsy:
Fig 1, 2: one area 100x, 200x
Fig 3, 4: the second area 100x, 200x
Fig 5: the third area 100x
What is your interpretation?
1. Figure5 is duct carcinoma in situ, of course. Morphology and immunostain results( smooth muscle myosin heavy chain is expressed by myoepthelial cells) support DCIS.
2. Figure 1-4 are invasive components with both p63 and smooth muscle myosin heavy chain negative
以下是引用Elizabeth在2009-2-25 17:15:00的发言: I don't think so. English is a very useful tool by which we communicate with others! I do not think it is enough just can read English paper. You can not publish paeper in Chinese in internation journal. |
Ok, you are a agressive or motivated girl or lady.Kidding.
If 5% pathologists in China can publish their original papers in the international journals, there will be a lot of.......
SMA stains
feel sorry to take too long for this case. Let us complete it today.
First case:
First area: both p63 and smooth muscle myosin heavy chain (SMMHC) are negative. All the tumor nests are invasive carcinoma.
The second area: smmhc is positive and p63 is negative. Smooth muscle actin is positive surrounding the large tumor nests. In addition, the morphologic features are like DCIS. So several large tumor nests are DCIS. In fact there are also some invasive components in the second area.