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B1757Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)

cqzhao 离线

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楼主 发表于 2009-01-06 08:24|举报|关注(0)
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We are in 2009 already. I send this easy case for you.

Breast core biopsy:

Fig 1, 2: one area 100x, 200x

Fig 3, 4: the second area 100x, 200x

Fig 5: the third area 100x

What is your interpretation?

  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图1
    图1
  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图2
    图2
  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图3
    图3
  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图4
    图4
  • Invasive ductal ca look as DCIS-the importance of myoepithelial marker (cqz-10)图5
    图5
标签:DCIS 乳腺浸润性导管癌
本帖最后由 于 2009-07-19 05:14:00 编辑
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Elizabeth 离线

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21 楼    发表于2009-01-28 20:41:00举报|引用
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 It's ok. We can practice English as well. Most of friends can read English in fact.
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牵手春天 离线

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22 楼    发表于2009-01-28 20:44:00举报|引用
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IDC & DCIS

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cqzhao 离线

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23 楼    发表于2009-02-12 11:22:00举报|引用
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 First area: the small tumor nests are invasive ca. Both p63 and smooth muscle myosin heavy chain are negative.

The second area: some large tumor nests are negative for p63 and positive for SMMHC. Should they are invasive or insitu?

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Elizabeth 离线

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24 楼    发表于2009-02-12 21:20:00举报|引用
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1. Figure5 is duct carcinoma in situ, of course. Morphology and immunostain results( smooth muscle myosin heavy chain is expressed by  myoepthelial cells) support DCIS.

2. Figure 1-4 are invasive components  with both p63 and  smooth muscle myosin heavy chain negative

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cqzhao 离线

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25 楼    发表于2009-02-15 21:07:00举报|引用
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本帖最后由 于 2009-02-15 21:10:00 编辑

 Before we conclude the above case, I  show you another case.

You diagnosis?


名称:图1
描述:图1
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cici 离线

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26 楼    发表于2009-02-16 17:04:00举报|引用
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 invasive  ductal carcinoma
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Elizabeth 离线

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27 楼    发表于2009-02-17 08:29:00举报|引用
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 I consider invasive duct carcinoma, however, immunostaining of myoepithelial markers  should be done.
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cqzhao 离线

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28 楼    发表于2009-02-18 07:38:00举报|引用
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以下是引用Elizabeth在2009-2-17 8:29:00的发言:

 I consider invasive duct carcinoma, however, immunostaining of myoepithelial markers  should be done.

Good thought
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cqzhao 离线

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29 楼    发表于2009-02-22 09:14:00举报|引用
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本帖最后由 于 2009-02-22 09:20:00 编辑

 This is P63 stain for the second case. You can appreciate the positive internal control. Smooth muscle myosin actin stain is negative also.

Clearly the second case is pure invasive ductal carcinoma.


名称:图1
描述:图1
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cqzhao 离线

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30 楼    发表于2009-02-22 09:21:00举报|引用
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 I will take a photo for SMA stain for the first case next week.
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Elizabeth 离线

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31 楼    发表于2009-02-22 12:25:00举报|引用
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  I am interested in your cases very much!  thank you.
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有福不在忙 离线

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32 楼    发表于2009-02-23 21:56:00举报|引用
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 p63怎么在癌巢中表达?

说说我对英语的看法:我不主张每个中国人都把英语学得很精,因为那样会浪费很多时间,人的精力是有限的。如果不是迫不得已,我是不会学英语的。现在我看老师们的英文帖子不是太费力,我认为这就够了。如果让美国大学生都必须通过汉语六级,我感觉美国经济很快就会落下来。

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有福不在忙

cqzhao 离线

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33 楼    发表于2009-02-25 11:47:00举报|引用
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本帖最后由 于 2009-02-25 11:47:00 编辑  Agree with above. It is enough if you can read some english papers. You can be a good pathologist in china even though you do not know English. 如果让美国大学生都必须通过汉语六级,我感觉美国经济很快就会落下来。Even though most of American students do not learn Chinese, American economic has fallen down already. I like your talk.
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Elizabeth 离线

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34 楼    发表于2009-02-25 17:15:00举报|引用
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 I don't think so. English is a very useful tool by which we communicate  with others! I do not think it is enough just can read English paper. You can not publish paeper in Chinese in internation journal.
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月新 离线

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35 楼    发表于2009-02-25 17:21:00举报|引用
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 学习病理不懂英文有一定的困难,这是事实。没有办法,谁让咱们发展慢。如果年龄大了,不想学了,也没有问题,你有什么需要,咱们网上雷锋多的很,大家可以翻译。
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cqzhao 离线

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36 楼    发表于2009-02-26 10:17:00举报|引用
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本帖最后由 于 2009-02-26 10:19:00 编辑
以下是引用Elizabeth在2009-2-25 17:15:00的发言:

 I don't think so. English is a very useful tool by which we communicate  with others! I do not think it is enough just can read English paper. You can not publish paeper in Chinese in internation journal.

Ok, you are a agressive or motivated girl or lady.Kidding.

If 5% pathologists in China can publish their original papers in the international journals, there will be a lot of....... 

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Elizabeth 离线

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37 楼    发表于2009-02-26 16:10:00举报|引用
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I just think English is a very useful tool .

In fact my English is poor, but I think I should do my best to learn it.

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Elizabeth 离线

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38 楼    发表于2009-02-26 20:04:00举报|引用
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You will find Elizabeth is a very kind lady, when I suddenly appear in front of you someday .

Kidding too.

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cqzhao 离线

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39 楼    发表于2009-02-27 11:22:00举报|引用
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 I am looking for
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cqzhao 离线

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40 楼    发表于2009-02-28 11:33:00举报|引用
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本帖最后由 于 2009-02-28 11:49:00 编辑

 SMA stains

feel sorry to take too long for this case. Let us complete it today.

First case:

First area: both p63 and smooth muscle myosin heavy chain (SMMHC) are negative. All the tumor nests are invasive carcinoma.

The second area: smmhc is positive and p63 is negative. Smooth muscle actin is positive surrounding the large tumor nests. In addition, the morphologic features are like DCIS. So several large tumor nests are DCIS. In fact there are also some invasive components in the second area.


名称:图1
描述:图1

名称:图2
描述:图2
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