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Work a long day and feel tired. Send you the most beautiful photos I once took.
It was my case of Pap when I was cyto fellow in the University of Southern California. I did not know what they were until my attending cytopathologist told me.
I am sure your guys know. Just for fun.
以下是引用小荷在2008-12-6 17:57:00的发言:
哇!漂亮!这副图应该发布到"病理学的艺术"专栏,风的影子,快来看! 大胆发言:多核巨嗜细胞 |
You are right about half. Righ about one cell with many nuclei.
What type? Think more. Do you see this kind of multinucleated macrophages?
More than 30 people saw the photos and only Xiaohe had interpretation. If every one give a different guess, I am sure one of the guesses will be right.
I will not tell you until some one writes the correct answer.
以下是引用hay在2008-12-7 11:24:00的发言: 合胞体滋养层细胞 (syncytial trophoblast)? |
呵呵继续.hay的回复是两个一半=一个,赵老师对吧 |
This afternoon I gave fellows two hours' lectures. I feel good to finish the duty. I went to the Gym and had 30 min swim. Life is beautiful.
Come here and become more happy to see that your guys had correct dx already.
These are two multinucleated giant cells called syncytiotrophoblasts. Most book mentioned they can have nuclei to to 50. In fact this cell here may have almost 100 nuclei. I did not find better cells than these two cells.
They detached from placenta so they can have tail. One cell looks like glove.
They can be confused with multinucleated histiocytes. Histiocytes are common in Pap smears, but syncytio are rare in Pap smears. Syncytiotrophoblasts show nuclei concentrated in the center of the cells (see above photos again); histiocytes are different. They may indicate early abortion if they occur in Pap during pregnancy. Of cause I think women will not have abortin in most case. You can mention in your report to ask physicins to pay attention.
This patient was a pregnant women with 7 months (may be).
Thanks,
cz
This afternoon I gave fellows two hours' lectures. I feel good to finish the duty. I went to the Gym and had 30 min swim. Life is beautiful.今天下午我给同行们讲了两个小时的课,感觉不错,圆满完成任务,然后我去了健身房,游泳三十分钟。生活多美好呀!
Come here and become more happy to see that your guys had correct dx already.来这看到大家的正确的回帖,更高兴了,
These are two multinucleated giant cells called syncytiotrophoblasts. 这是两个多核巨细胞被称为合体滋养叶细胞,Most book mentioned they can have nuclei to to 50.多数书上介绍 核可以是50个,In fact this cell here may have almost 100 nuclei. 实际上至少可以有100个核I did not find better cells than these two cells.我看这两个细胞非常漂亮,没有比她们俩更漂亮的细胞了。
They detached from placenta so they can have tail. 她们从胎盘分离下来,所以有尾巴,One cell looks like glove.有一个细胞象手套。They can be confused with multinucleated histiocytes. 有时可能被误认为是多核组织细胞,Histiocytes are common in Pap smears, but syncytio are rare in Pap smears. 宫颈涂片常见组织细胞,但是合体细胞是很罕见的。Syncytiotrophoblasts show nuclei concentrated in the center of the cells (see above photos again); 如图所示,合体滋养叶细胞的核位于中间,histiocytes are different. 这样与组织细胞容易区分,组织细胞的核常位于外周,They may indicate early abortion if they occur in Pap during pregnancy. 宫颈涂片出现了这样的细胞提示为早期流产。Of cause I think women will not have abortin in most case. You can mention in your report to ask physicins to pay attention.当然多数情况下出现这种细胞患者并没有出现流产。因此你的病理报告中应该提出有这种细胞,表示怀孕,应该注意。
This patient was a pregnant women with 7 months (may be). 本例病人怀孕七个月。
Thanks,感谢大家。
以下是引用cqzhao在2008-12-10 12:57:00的发言:
These are two multinucleated giant cells called syncytiotrophoblasts. Most book mentioned they can have nuclei to to 50. In fact this cell here may have almost 100 nuclei. I did not find better cells than these two cells. They detached from placenta so they can have tail. One cell looks like glove. They can be confused with multinucleated histiocytes. Histiocytes are common in Pap smears, but syncytiotrophoblasts are rare in Pap smears. Syncytiotrophoblasts show nuclei concentrated in the center of the cells (see above photos again); histiocytes are different. They may indicate early abortion if they occur in Pap during pregnancy. Of cause I think women will not have abortin in most case. You can mention in your report to ask physicins to pay attention. This patient was a pregnant women with 7 months (may be). Thanks, cz |