| 图片： | |
|---|---|
| 名称： | |
| 描述： | |
- B1730乳腺肿物
图1
图2
图3
图4
图5
图6
图7
| 姓 名： | ××× | 性别： | 女26 | 年龄： | |
| 标本名称： | 左乳腺肿物一年 | ||||
| 简要病史： | |||||
| 肉眼检查： | 肿物8.5*6.5*4.5切面囊性囊内充满干酪样物, | ||||
标签：乳腺颗粒细胞瘤 组织细胞肿瘤 分泌性癌
相关帖子
- • 右乳肿块－ 分泌性癌
- • 乳腺肿瘤
- • 乳腺肿物
- • 20090807-乳腺肿块
- • 左乳头皮下肿物 免疫组化已上传 欢迎讨论
- • 少见乳腺肿物,大家快来瞧瞧啊!
×参考诊断
-
stevenshen 离线
- 帖子：343
- 粉蓝豆：2
- 经验：343
- 注册时间：2008-06-03
- 加关注 | 发消息
Interesting case.
I cannot see the tumor edge in above photos. My differential dx includes ruptured cysts with a granulomatous reaction, a histiocytic tumor, apocrin carcinoma, and granular cell tumor (GCT). The cytomorphology of the last two photos are really consistent with GCT.
Suggest IHC:
Pan cytokeratin, EMA: mammary ca is positive, histiocyte or GCT is negative
S-100: strongly positive for GCT
alpha-antitrypsin: Histiocytes are positive, GCT is negative.
CD68: Strongly and diffusely positive for histiocyte; GCT may be focal positive or negative
Hope to see your follow-up
-
ZQH19811029 离线
- 帖子：458
- 粉蓝豆：1
- 经验：458
- 注册时间：2009-11-15
- 加关注 | 发消息
| 以下是引用cqzhao在2008-11-21 11:13:00的发言：
Interesting case. I cannot see the tumor edge in above photos. My differential dx includes ruptured cysts with a granulomatous reaction, a histiocytic tumor, apocrin carcinoma, and granular cell tumor (GCT). The cytomorphology of the last two photos are really consistent with GCT. Suggest IHC: Pan cytokeratin, EMA: mammary ca is positive, histiocyte or GCT is negative S-100: strongly positive for GCT alpha-antitrypsin: Histiocytes are positive, GCT is negative. CD68: Strongly and diffusely positive for histiocyte; GCT may be focal positive or negative Hope to see your follow-up
大概翻译: 上述图片中我看不到肿瘤的边界, 我认为需要鉴别的鉴别诊断包括囊肿破裂引起的肉芽肿反应; 组织细胞肿瘤, 分泌性癌, 颗粒细胞瘤 最后两张的图片上看该细胞形态学,符合颗粒细胞瘤. 建议免疫组化: CK-P,EMA乳腺癌是阳性的,组织细胞或颗粒细胞是阴性的 S-100: 颗粒细胞为强阳性 alpha-antitrypsin 组织细胞是阳性的,颗粒细胞是阴性的 CD68: 组织细胞是广泛的强阳性,颗粒细胞是局灶的阳性或阴性的
|
