Histology. Adenocarcinoma. Clear cell carcinoma. Cannot tell the origin, endocervical vs endometrial vs metastatic from ovary or other orgains. Need to know clinical information and imaging result. Of cause mostly it is from endometrial or endocervical origin.

This is a truely interesting case. Thanks.

 

 宫颈多点活检，阴性

 Should have endometrial sampling too

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以下是引用cqzhao在2008-11-6 18:40:00的发言：  Should have endometrial sampling too

是的

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 If endoemtrial sample is negative for ca. The patient should have at least a leep/cone biosy for diagnosis purpose. I cannot appreciate the relation of clear cell carcinoma to the normal cervical tissue in histology photos. Is the carcinoma only limited in the polyp? or the entire polyp (called clinically) is a polypoid tumor mass.  Also be aware that the metastatic clear cell carcinoma (CCC) from ovary, bladder, kidney et al can has the exact same morphology as that of cervical or endometrial ccc. Imaging study is needed for this case. You can also try to stain ER/PR. if ER or PR is positive, the tumor is from gyn tract. However if it is negative for er/pr, the results are useless because a lot gynecologic CCCs can be negative for ER/PR.

腺上皮异常，建议活检。

 

 谢谢赵老师的关注,

宫颈活检虽然阴性,但是宫颈组织切片上飘浮着个别异形透明细胞,息肉根部有坏死物,见不到透明细胞癌.

有一个值得注意的病史,病人月经期间常有"块状组织脱落"(病人后来口述),B超子宫内膜增厚,目前尚未诊刮

免疫组化暂时还没做

一定继续跟踪,再次感谢

 学习了，谢谢

 看完这些,真的收益很多.像在听大师讲课.

 可以肯定出细胞学腺癌诊断

 谢谢全子！谢谢赵老师！我从中学到很多东西！再次感谢您们精彩的讲解和无私的奉献！

临床报的话建议这种还是保守点吧，AGC不除外腺癌，给自己留条退路。

 这个病人活检阴性,也应密切随访

 学习了，谢谢！

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